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Title:
ANTI-ROR1 ANTIBODIES
Document Type and Number:
WIPO Patent Application WO/2024/008112
Kind Code:
A1
Abstract:
Provided are antibodies and antigen-binding fragments thereof that recognize ROR1. In some embodiments, the antibodies provide a means of treating ROR1-positive cancer. In some embodiments, the antibodies are used to diagnose or image ROR1-positive cancer.

Inventors:
ZHAO JIANXUN (CN)
NIE CUI (CN)
WANG ZHENG (CN)
GAO YUE (CN)
ZHAO CHUCHU (CN)
ZHU GUANGBEI (CN)
HOU JIANHAO (CN)
YANG YUANYUAN (CN)
Application Number:
PCT/CN2023/105835
Publication Date:
January 11, 2024
Filing Date:
July 05, 2023
Export Citation:
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Assignee:
NONA BIOSCIENCES SUZHOU CO LTD (CN)
International Classes:
A61K35/00; C07K16/28; A61K39/395
Domestic Patent References:
WO2021159029A12021-08-12
WO2022129622A12022-06-23
Foreign References:
CN111670045A2020-09-15
CN107428833A2017-12-01
US20210069342A12021-03-11
Other References:
ZHAO YUMING, ZHANG DENGYANG, GUO YAO, LU BO, ZHAO ZHIZHUANG JOE, XU XIAOJUN, CHEN YUN: "Tyrosine Kinase ROR1 as a Target for Anti-Cancer Therapies", FRONTIERS IN ONCOLOGY, FRONTIERS RESEARCH FOUNDATION, CH, vol. 11, 28 May 2021 (2021-05-28), CH , pages 680834, XP093126376, ISSN: 2234-943X, DOI: 10.3389/fonc.2021.680834
Attorney, Agent or Firm:
LIU, SHEN & ASSOCIATES (CN)
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