Title:
FORMAMIDE-SUBSTITUTED HETEROTRICYCLIC DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/008113
Kind Code:
A1
Abstract:
The present invention relates to a formamide-substituted heterotricyclic derivative represented by formula (I), a method for preparing same, and use thereof. The present invention further relates to a pharmaceutical composition comprising the compound as an active ingredient and use of the compound or the pharmaceutical composition in treating and/or preventing a related disease mediated by PRMT5.
Inventors:
LIU GANG (CN)
XIA SHANGHUA (CN)
LI JIAN (CN)
WANG YING (CN)
ZENG HONG (CN)
GONG XIAOMING (CN)
PAN DESI (CN)
LU XIANPING (CN)
XIA SHANGHUA (CN)
LI JIAN (CN)
WANG YING (CN)
ZENG HONG (CN)
GONG XIAOMING (CN)
PAN DESI (CN)
LU XIANPING (CN)
Application Number:
PCT/CN2023/105842
Publication Date:
January 11, 2024
Filing Date:
July 05, 2023
Export Citation:
Assignee:
SHENZHEN CHIPSCREEN BIOSCIENCES CO LTD (CN)
CHENGDU CHIPSCREEN PHARMACEUTICAL LTD (CN)
CHENGDU CHIPSCREEN PHARMACEUTICAL LTD (CN)
International Classes:
C07D471/04; A61K31/4355; A61K31/437; A61K31/501; A61P35/00; C07D401/00; C07D471/14; C07D491/048; C07D491/147; C07D495/04; C07D498/04; C07D498/14
Domestic Patent References:
| WO2022115377A1 | 2022-06-02 | |||
| WO2015049629A1 | 2015-04-09 | |||
| WO2017153515A1 | 2017-09-14 | |||
| WO2020205660A1 | 2020-10-08 |
Foreign References:
| CN108137586A | 2018-06-08 | |||
| CN102917590A | 2013-02-06 |
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