Title:
ANTIBACTERIALS DIASCCHARIDE DERIVATIVES
Document Type and Number:
WIPO Patent Application WO1999061913
Kind Code:
A3
Abstract:
Disclosed is an isolated compound having the structure shown in Figure 2, wherein n is an integer between 3 and 10 (inclusive) and X may be H, OH, alkyl, aryl, amyl, or an amino acid residue (optionally substituted) or a sugar residue (optionally substituted), and wherein R and R<1> are hydrophobic hydrocarbon or fatty acid chains (R may be the same as R<1> or different), a method of preparing compositions comprising the compound, and a diagnostic method comprising use of the composition.
Inventors:
LAMBERT PETER ANTHONY (GB)
ELLIOTT THOMAS STUART JACKSON (GB)
ELLIOTT THOMAS STUART JACKSON (GB)
Application Number:
PCT/GB1999/001650
Publication Date:
April 19, 2001
Filing Date:
May 26, 1999
Export Citation:
Assignee:
OXOID LTD (GB)
LAMBERT PETER ANTHONY (GB)
ELLIOTT THOMAS STUART JACKSON (GB)
LAMBERT PETER ANTHONY (GB)
ELLIOTT THOMAS STUART JACKSON (GB)
International Classes:
A61K31/70; A61K39/085; C07H3/04; C07K1/00; C07K16/12; C12N1/20; (IPC1-7): C07H3/04; C07K1/00; A61K31/70; C12N15/06; C12N1/20; A61K39/085; C07K16/12
Domestic Patent References:
| WO1997042343A2 | 1997-11-13 |
Other References:
J.J.OLTVOORT ET AL.: "Synthesis of a Lipoteichoic Acid-Carrier Fragment of Staphylococcus aureus.", CARBOHYDRATE RESEARCH., vol. 130, 1984, ELSEVIER SCIENTIFIC PUBLISHING COMPANY. AMSTERDAM., NL, pages 147 - 163, XP002120748, ISSN: 0008-6215
W.FISCHER: "Molecular Analysis of Lipid Macroamphiphiles by Hydrophobic Interaction Chromatography Exemplified with Lipotechoic Acids.", ANALYTICAL CHEMISTRY, vol. 208, 1993, pages 49 - 56, XP002120749
H.I.WERGELAND ET AL.: "Antibodies to Staphylococcal Peptidoglycan and its Peptide Epitopes, Techoic Acid, and Lipotechoic Acid in Sera from Blood Donors and Patients with Staphylococcal Infections.", JOURNAL OF CLINICAL MICROBIOLOGY, vol. 27, no. 6, June 1989 (1989-06-01), pages 1286 - 1291, XP002120750
J.J.OLTVOORT ET AL.: "A Simple Approach to the Synthesis of a Membrane Techoic Acid Fragment of Staphylococcus aureus.", RECUEIL, JOURNAL OF THE ROYAL NETHERLANDS CHEMICAL SOCIETY, vol. 101, no. 3, March 1982 (1982-03-01), pages 87 - 91, XP002120751
DATABASE WPI Section Ch Week 198703, Derwent World Patents Index; Class B04, AN 1987-017786, XP002120752
W.FISCHER: "Molecular Analysis of Lipid Macroamphiphiles by Hydrophobic Interaction Chromatography Exemplified with Lipotechoic Acids.", ANALYTICAL CHEMISTRY, vol. 208, 1993, pages 49 - 56, XP002120749
H.I.WERGELAND ET AL.: "Antibodies to Staphylococcal Peptidoglycan and its Peptide Epitopes, Techoic Acid, and Lipotechoic Acid in Sera from Blood Donors and Patients with Staphylococcal Infections.", JOURNAL OF CLINICAL MICROBIOLOGY, vol. 27, no. 6, June 1989 (1989-06-01), pages 1286 - 1291, XP002120750
J.J.OLTVOORT ET AL.: "A Simple Approach to the Synthesis of a Membrane Techoic Acid Fragment of Staphylococcus aureus.", RECUEIL, JOURNAL OF THE ROYAL NETHERLANDS CHEMICAL SOCIETY, vol. 101, no. 3, March 1982 (1982-03-01), pages 87 - 91, XP002120751
DATABASE WPI Section Ch Week 198703, Derwent World Patents Index; Class B04, AN 1987-017786, XP002120752
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