Title:
ANTIBODY AGAINST HUMAN KGF
Document Type and Number:
WIPO Patent Application WO/2001/079265
Kind Code:
A1
Abstract:
A polyclonal antibody specifically binding to human keratinocyte growth factor (KGF). Because of having a high specificity to KGF, this antibody makes it possible to accurately and quickly detect and determine KGF in various organs, tissues and cells. Thus, it is usable in detecting and immunoassaying various tumors such as pearl tumor.
Inventors:
KOJI TAKEHIKO (JP)
NAKAMURA MITSURU (JP)
NAKAMURA MITSURU (JP)
Application Number:
PCT/JP2000/008693
Publication Date:
October 25, 2001
Filing Date:
December 08, 2000
Export Citation:
Assignee:
NICHIREI KK (JP)
KOJI TAKEHIKO (JP)
NAKAMURA MITSURU (JP)
KOJI TAKEHIKO (JP)
NAKAMURA MITSURU (JP)
International Classes:
C12N15/09; C07K7/08; C07K16/22; C12P21/08; G01N33/574; C12R1/91; (IPC1-7): C07K7/08; C07K16/22; G01N33/53; G01N33/68
Domestic Patent References:
| WO1990008771A1 | 1990-08-09 |
Other References:
FINCH PAUL W. ET AL.: "Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth", SCIENCE, vol. 245, 18 August 1989 (1989-08-18), pages 752 - 754, XP002937855
BAJAJ-ELLIOTT MONA ET AL.: "Interaction between stromal cell-derived keratinocyte growth factor and epithelial transforming growth factor in immune-mediated crypt cell hyperplasia", THE JOURNAL OF CLINICAL INVESTIGATION, vol. 102, no. 8, 15 October 1998 (1998-10-15), pages 1473 - 1480, XP002937856
ALARID ELAINE T. ET AL.: "Keratinocyte growth factor functions in epithelial induction during seminal vesicle development", PROC. NATL. ACAD. SCI. USA, vol. 91, no. 3, February 1994 (1994-02-01), pages 1074 - 1078, XP002937857
PANOS RALPH J. ET AL.: "Keratinocyte growth factor and hepatocyte growth factor / scatter factor are heparin-binding growth factors for alveolar type II cells in fibroblast-conditioned medium", THE JOURNAL OF CLINICAL INVESTIGATION, vol. 92, no. 2, August 1993 (1993-08-01), pages 969 - 977, XP002937858
BAJAJ-ELLIOTT MONA ET AL.: "Interaction between stromal cell-derived keratinocyte growth factor and epithelial transforming growth factor in immune-mediated crypt cell hyperplasia", THE JOURNAL OF CLINICAL INVESTIGATION, vol. 102, no. 8, 15 October 1998 (1998-10-15), pages 1473 - 1480, XP002937856
ALARID ELAINE T. ET AL.: "Keratinocyte growth factor functions in epithelial induction during seminal vesicle development", PROC. NATL. ACAD. SCI. USA, vol. 91, no. 3, February 1994 (1994-02-01), pages 1074 - 1078, XP002937857
PANOS RALPH J. ET AL.: "Keratinocyte growth factor and hepatocyte growth factor / scatter factor are heparin-binding growth factors for alveolar type II cells in fibroblast-conditioned medium", THE JOURNAL OF CLINICAL INVESTIGATION, vol. 92, no. 2, August 1993 (1993-08-01), pages 969 - 977, XP002937858
Attorney, Agent or Firm:
Hiraki, Yusuke (Toranomon 1-chome Minato-ku, Tokyo, JP)
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