Title:
ANTIBODY-DRUG CONJUGATES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS
Document Type and Number:
WIPO Patent Application WO/2024/037503
Kind Code:
A1
Abstract:
Provided herein are antibody-drug conjugates, for example, a compound of Formula (I), and pharmaceutical compositions thereof. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a proliferative disease. Additionally, provided herein are functionalized compounds, for example, a compound of Formula (IA), for conjugation with an antibody.
Inventors:
FU HONG (US)
ZHONG ZIYANG (US)
ZHONG ZIYANG (US)
Application Number:
PCT/CN2023/112924
Publication Date:
February 22, 2024
Filing Date:
August 14, 2023
Export Citation:
Assignee:
SHANGHAI RUOTUO BIOSCIENCES CO LTD (CN)
International Classes:
A61K47/68; A61K31/437; A61K31/4745; A61K39/44; A61P35/00; C07D491/14
Domestic Patent References:
| WO2022140504A1 | 2022-06-30 | |||
| WO2014067960A2 | 2014-05-08 | |||
| WO2022072538A1 | 2022-04-07 |
Foreign References:
| CN112707916A | 2021-04-27 |
Attorney, Agent or Firm:
J.Z.M.C. PATENT AND TRADEMARK LAW OFFICE (GENERAL PARTNERSHIP) (CN)
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