Title:
ANTIFUNGAL EYE DROP
Document Type and Number:
WIPO Patent Application WO/2023/140275
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing an antifungal eye drop, particularly, an aqueous eye drop, the eye drop containing luliconazole as an active ingredient. The problem is solved by the eye drop which contains: 1) luliconazole; 2) benzyl alcohol; and 3) one or two selected from polyoxyethylene polyoxypropylene glycol and polyoxyethylene hydrogenated castor oil.
Inventors:
ITO MADOKA (JP)
ARIMOTO SHO (JP)
TODOKORO DAISUKE (JP)
ARIMOTO SHO (JP)
TODOKORO DAISUKE (JP)
Application Number:
PCT/JP2023/001285
Publication Date:
July 27, 2023
Filing Date:
January 18, 2023
Export Citation:
Assignee:
NIHON NOHYAKU CO LTD (JP)
UNIV GUNMA NAT UNIV CORP (JP)
UNIV GUNMA NAT UNIV CORP (JP)
International Classes:
A61K9/08; A61K31/4178; A61K47/10; A61P27/02; A61P31/10
Domestic Patent References:
| WO2019070221A1 | 2019-04-11 |
Foreign References:
| JP2014152135A | 2014-08-25 |
Other References:
TAKASHI SUZUKI, DAISUKE TODOKORO, KOICHI MAKIMURA, HIROAKI NAGAI, RYO SHIOMI, YUSAKU NISHIDOI, YUICHI HORI: "GK-05-5: Examination of toxicity of 1% luliconazole eye drops", FOURSOME 2018 TOKYO PROGRAM AND LECTURE ABSTRACTS; 55TH JAPANESE SOCIETY FOR EYE INFECTIOUS DISEASES: JULY 14TH (SAT) - 15TH (SUN), 2018, JAPANESE SOCIETY OF OCULAR INFECTIOUS DISEASES, JP, 14 July 2018 (2018-07-14), JP, XP009548016
DAISUKE TODOKORO, TAKASHI SUZUKI, SHUN TAMURA, KOICHI MAKIMURA, HIDEYO YAMAGUCHI, HIDEO AKIYAMA: "GK-05-4 Antifungal activity of luliconazole against Fusarium isolated from keratitis", FOURSOME 2018 TOKYO PROGRAM AND LECTURE ABSTRACTS; 55TH JAPANESE SOCIETY FOR EYE INFECTIOUS DISEASES: JULY 14TH (SAT) - 15TH (SUN), 2018, JAPANESE SOCIETY OF OCULAR INFECTIOUS DISEASES, JP, 14 July 2018 (2018-07-14), JP, pages 68, XP009548017
TOMOHIKO SAITO, TAKASHI SUZUKI, DAISUKE TODOKORO, YUICHI HORI: "GK-O5-5 Examination of toxicity of antifungal drugs to cultured corneal epithelial cells", FOURSOME 2021 SENDAI PROGRAM/LECTURE ABSTRACTS; 57TH JAPANESE SOCIETY FOR EYE INFECTIOUS DISEASES: FRIDAY, JULY 23, 2021 - SATURDAY, JULY 24, 2021 , 23 July 2021 (2021-07-23), JP, pages 69, XP009548018
DAISUKE TODOKORO, TAKASHI SUZUKI, SHUN TAMURA, KOICHI MAKIMURA, HIDEYO YAMAGUCHI, HIDEO AKIYAMA: "GK-05-4 Antifungal activity of luliconazole against Fusarium isolated from keratitis", FOURSOME 2018 TOKYO PROGRAM AND LECTURE ABSTRACTS; 55TH JAPANESE SOCIETY FOR EYE INFECTIOUS DISEASES: JULY 14TH (SAT) - 15TH (SUN), 2018, JAPANESE SOCIETY OF OCULAR INFECTIOUS DISEASES, JP, 14 July 2018 (2018-07-14), JP, pages 68, XP009548017
TOMOHIKO SAITO, TAKASHI SUZUKI, DAISUKE TODOKORO, YUICHI HORI: "GK-O5-5 Examination of toxicity of antifungal drugs to cultured corneal epithelial cells", FOURSOME 2021 SENDAI PROGRAM/LECTURE ABSTRACTS; 57TH JAPANESE SOCIETY FOR EYE INFECTIOUS DISEASES: FRIDAY, JULY 23, 2021 - SATURDAY, JULY 24, 2021 , 23 July 2021 (2021-07-23), JP, pages 69, XP009548018
Attorney, Agent or Firm:
ASAMURA IP P.C. (JP)
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