Title:
APOPTOSIS INDUCING PROTEIN AND GENE ENCODING THE SAME
Document Type and Number:
WIPO Patent Application WO/1997/040143
Kind Code:
A1
Abstract:
An apoptosis inducing protein (ASK1) or derivatives thereof, having a protein kinase activity and enhancing an SEK1 kinase activity and/or MKK3 kinase activity; a base sequence encoding the same; and a malignant tumor remedy comprising the same.
Inventors:
MIYAZONO KOHEI (JP)
ICHIJO HIDENORI (JP)
ICHIJO HIDENORI (JP)
Application Number:
PCT/JP1997/001348
Publication Date:
October 30, 1997
Filing Date:
April 18, 1997
Export Citation:
Assignee:
JAPAN FOUND CANCER (JP)
MIYAZONO KOHEI (JP)
ICHIJO HIDENORI (JP)
MIYAZONO KOHEI (JP)
ICHIJO HIDENORI (JP)
International Classes:
C12N15/09; A61K38/00; A61K39/395; A61K48/00; A61P35/00; C07H21/04; C07K14/47; C07K16/00; C07K16/40; C12N1/19; C12N1/21; C12N5/00; C12N5/10; C12N9/12; C12N15/54; C12P21/02; C12P21/08; C12R1/91; (IPC1-7): C12N9/12; C12N15/54; C12N1/19; C12N1/21; C12N5/00; C12P21/02; A61K38/45; A61K48/00; C07K16/40
Other References:
THE JOURNAL OF BIOLOGICAL CHEMISTRY, Vol. 271, No. 49, (06-12-1996), pages 31607-31611.
SCIENCE, Vol. 275, (3 January 1997), pages 90-94.
THE JOURNAL OF BIOLOGICAL CHEMISTRY, Vol. 271, No. 10, (08-03-1996), pages 5361-5368.
SCIENCE, Vol. 275, (3 January 1997), pages 90-94.
THE JOURNAL OF BIOLOGICAL CHEMISTRY, Vol. 271, No. 10, (08-03-1996), pages 5361-5368.
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