Title:
APPLICATION OF CHIDAMIDE IN COMBINATION WITH R-CHOP, AND DRUG COMBINATION
Document Type and Number:
WIPO Patent Application WO/2020/103788
Kind Code:
A1
Abstract:
The present invention provides an application of chidamide in combination with R-CHOP in preparing a drug used for treating B-cell lymphoma, and also provides a drug comprising chidamide and R-CHOP. Chidamide in combination with R-CHOP has a synergistic therapeutic effect on B-cell lymphoma.
Inventors:
LU XIANPING (CN)
ZHAO WEILI (CN)
FU XIN (CN)
XU PENGPENG (CN)
LIU TING (CN)
ZHAO WEILI (CN)
FU XIN (CN)
XU PENGPENG (CN)
LIU TING (CN)
Application Number:
PCT/CN2019/119170
Publication Date:
May 28, 2020
Filing Date:
November 18, 2019
Export Citation:
Assignee:
SHENZHEN CHIPSCREEN BIOSCIENCES CO LTD (CN)
RUIJIN HOSPITAL AFFILIATED TO THE SHANGHAI JIAO TONG UNIV MEDICAL SCHOOL (CN)
RUIJIN HOSPITAL AFFILIATED TO THE SHANGHAI JIAO TONG UNIV MEDICAL SCHOOL (CN)
International Classes:
A61K31/44; A61K31/475; A61K31/573; A61K31/675; A61K31/704; A61K39/395; A61P35/00
Foreign References:
| CN201811394614A | 2018-11-20 |
Other References:
ZHANG PEIPEI: "Mechanisms of Chidamide in Diffuse Large B-cell Lymphoma Cell Lines with Distinctive Proliferative Characteristics", CHINESE MASTER'S THESES FULL-TEXT DATABASE, 1 May 2016 (2016-05-01), pages 1 - 66, XP055817958
LI LUKE : "Clinical Observation of R-CHOP Regimen in the Treatment of 36 Cases of Diffuse Large B-cell Lymphoma", JOURNAL OF COMMUNITY MEDICINE, vol. 15, no. 12, 30 June 2017 (2017-06-30), pages 31 - 32, XP009528419
See also references of EP 3884943A4
LI LUKE : "Clinical Observation of R-CHOP Regimen in the Treatment of 36 Cases of Diffuse Large B-cell Lymphoma", JOURNAL OF COMMUNITY MEDICINE, vol. 15, no. 12, 30 June 2017 (2017-06-30), pages 31 - 32, XP009528419
See also references of EP 3884943A4
Attorney, Agent or Firm:
SHENPAT INTELLECTUAL PROPERTY AGENCY (CN)
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