Title:
AQUEOUS PREPARATION CONTAINING ANTIVIRAL AGENT HAVING PURINE OR PYRIMIDINE SKELETON
Document Type and Number:
WIPO Patent Application WO/1999/016447
Kind Code:
A1
Abstract:
An aqueous preparation which is used as a liquid preparation such as an eye drop or nasal drop for infectious diseases attributable to herpesvirus, etc., contains as the active ingredient an antiviral agent having a purine or pyrimidine skeleton, and is prevented from untergoing crystal precipitation in a physiologically acceptable pH range. The aqueous preparation contains a crystal precipitation inhibitor to keep the drug dissolved in the physiologically acceptable pH range and thus prevent crystal precipitation.
Inventors:
SUZUKI HIDEKAZU (JP)
OGAWA HIROYUKI (JP)
TAKEUCHI MASANOBU (JP)
SAITO YOSHIAKI (JP)
OGAWA HIROYUKI (JP)
TAKEUCHI MASANOBU (JP)
SAITO YOSHIAKI (JP)
Application Number:
PCT/JP1998/004333
Publication Date:
April 08, 1999
Filing Date:
September 28, 1998
Export Citation:
Assignee:
WAKAMOTO PHARMA CO LTD (JP)
SUZUKI HIDEKAZU (JP)
OGAWA HIROYUKI (JP)
TAKEUCHI MASANOBU (JP)
SAITO YOSHIAKI (JP)
SUZUKI HIDEKAZU (JP)
OGAWA HIROYUKI (JP)
TAKEUCHI MASANOBU (JP)
SAITO YOSHIAKI (JP)
International Classes:
A61K9/00; A61K9/08; A61K31/505; A61K31/52; A61K47/38; (IPC1-7): A61K31/505; A61K9/08; A61K31/52; A61K47/38
Foreign References:
| JPH08268892A | 1996-10-15 | |||
| JPH07247216A | 1995-09-26 |
Other References:
CHEN A. X., ZITO S. W., NASH R. A.: "SOLUBILITY ENHANCEMENT OF NUCLEOSIDES AND STRUCTURALLY RELATED COMPOUNDS BY COMPLEX FORMATION.", PHARMACEUTICAL RESEARCH, SPRINGER NEW YORK LLC, US, vol. 11., no. 03., 1 January 1994 (1994-01-01), US, pages 398 - 401., XP002915350, ISSN: 0724-8741, DOI: 10.1023/A:1018913104383
Attorney, Agent or Firm:
Nakamura, Minoru (Room 646 3-1, Marunouchi 3-chome Chiyoda-ku Tokyo, JP)
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