Title:
AROMATIC ACETYLENE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/067812
Kind Code:
A1
Abstract:
The present invention relates to an aromatic acetylene derivative, a preparation method therefor, and a medical use of a pharmaceutical composition containing said derivative. Specifically, the present invention relates to an aromatic acetylene derivative represented by general formula (I), a preparation method therefor, a pharmaceutically acceptable salt thereof, and a use thereof as therapeutic agents, particularly LPXC inhibitors, the definitions of the substituents in the general formula (I) being the same as those in the description.
Inventors:
HUANG XIANGUI (CN)
LIAO WEIWEI (CN)
WU CHENGFEI (CN)
YE CHENG (CN)
XU DAIWANG (CN)
XU XIAOJIE (CN)
ZHOU HOUJIANG (CN)
LIAO WEIWEI (CN)
WU CHENGFEI (CN)
YE CHENG (CN)
XU DAIWANG (CN)
XU XIAOJIE (CN)
ZHOU HOUJIANG (CN)
Application Number:
PCT/CN2023/122622
Publication Date:
April 04, 2024
Filing Date:
September 28, 2023
Export Citation:
Assignee:
ZHEJIANG HISUN PHARM CO LTD (CN)
SHANGHAI ARYL PHARMTECH CO LTD (CN)
SHANGHAI ARYL PHARMTECH CO LTD (CN)
International Classes:
C07D413/14; A61K31/422; A61K31/438; A61K31/4439; A61P31/04
Attorney, Agent or Firm:
SINO-CREATIVITY INTELLECTUAL PROPERTY LAW FIRM (CN)
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