Title:
AROMATIC AMINE DERIVATIVES AND PREPARATION METHOD AND MEDICAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/078241
Kind Code:
A1
Abstract:
The invention relates to aromatic amine derivatives, and a preparation method and medical use thereof. In particular, the invention relates to a compound represented by general formula (I), a preparation method therefor, a pharmaceutical composition containing same, and a use thereof as a Toll like receptor (TLR) agonist for the treatment of diseases related to TLR8 activity. The definitions of each group in general formula (I) are the same as those in the description.
Inventors:
YAN XU (CN)
TIAN WEIXUE (CN)
CHEN SHIZHU (CN)
YIN HUIJUN (CN)
TIAN WEIXUE (CN)
CHEN SHIZHU (CN)
YIN HUIJUN (CN)
Application Number:
PCT/CN2022/128963
Publication Date:
May 11, 2023
Filing Date:
November 01, 2022
Export Citation:
Assignee:
THE NAT INSTITUTES OF PHARMACEUTICAL R&D CO LTD (CN)
International Classes:
C07D471/04; A61K31/519; A61P31/14; A61P31/18; A61P35/00
Domestic Patent References:
| WO2020007275A1 | 2020-01-09 | |||
| WO2020057604A1 | 2020-03-26 | |||
| WO2020078455A1 | 2020-04-23 |
Foreign References:
| CN107108615A | 2017-08-29 | |||
| CN108069963A | 2018-05-25 | |||
| CN109923106A | 2019-06-21 |
Attorney, Agent or Firm:
GE CHENG & CO.,LTD. (CN)
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