Title:
AROMATIC COMPOUND AND APPLICATION THEREOF IN ANTITUMOR DRUG
Document Type and Number:
WIPO Patent Application WO/2022/028346
Kind Code:
A1
Abstract:
An aromatic compound protein inhibitor, a stereoisomer, a tautomer, or a pharmaceutically acceptable salt thereof, a method related to the preparation and use of the compound, a pharmaceutical composition comprising the compound, and a relevant cancer treatment method. The aromatic compound has selective and significant inhibitory activity on a protein, and has a wide application prospect in the field of tumor treatment.
Inventors:
ZHANG QIANG (CN)
DU FENGTIAN (CN)
WANG HAIBO (CN)
GUO NA (CN)
ZHANG TAO (CN)
DU FENGTIAN (CN)
WANG HAIBO (CN)
GUO NA (CN)
ZHANG TAO (CN)
Application Number:
PCT/CN2021/109963
Publication Date:
February 10, 2022
Filing Date:
August 02, 2021
Export Citation:
Assignee:
SHANGHAI ZHEYE BIOTECHNOLOGY CO LTD (CN)
International Classes:
C07D403/04; A61K31/517; A61K31/519; A61P35/00; C07D471/04; C07D487/04
Domestic Patent References:
| WO2019051291A1 | 2019-03-14 | |||
| WO2018217651A1 | 2018-11-29 | |||
| WO2019051291A1 | 2019-03-14 | |||
| WO2020050890A2 | 2020-03-12 | |||
| WO2020102730A1 | 2020-05-22 | |||
| WO2018217651A1 | 2018-11-29 |
Foreign References:
| US20190374542A1 | 2019-12-12 | |||
| CN110366550A | 2019-10-22 | |||
| CN106488910A | 2017-03-08 | |||
| CN111377918A | 2020-07-07 | |||
| CN111205286A | 2020-05-29 | |||
| US20190343838A1 | 2019-11-14 | |||
| CN103265498A | 2013-08-28 | |||
| US20190374542A1 | 2019-12-12 | |||
| JPS61282089A | 1986-12-12 | |||
| US20030148480A1 | 2003-08-07 |
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JOURNAL OF BIOSCIENCES (BANGALORE, INDIA, vol. 34, no. 1, 2009, pages 21 - 26
THE NEW ENGLAND JOURNAL OF MEDICINE, vol. 383, 2020, pages 1207 - 1217
TETRAHEDRON LETTER, 1976, pages 3013 - 3016
ORGANIC LETTERS, vol. 20, no. 7, 2018, pages 1712 - 1715
SYNLETT, vol. 31, no. 7, 2020, pages 699 - 702
ORGANIC LETTERS, vol. 21, no. 7, 2019, pages 2231 - 2235
ORGANOMETALLICS, vol. 38, no. 1, 2019, pages 119 - 128
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 143, no. 1, 2021, pages 53 - 59
ORGANIC PROCESS RESEARCH & DEVELOPMEN, vol. 21, no. 11, 2017, pages 1741 - 1744
JOURNAL OF BIOSCIENCES (BANGALORE, INDIA, vol. 34, no. 1, 2009, pages 21 - 26
THE NEW ENGLAND JOURNAL OF MEDICINE, vol. 383, 2020, pages 1207 - 1217
Attorney, Agent or Firm:
SINO-CREATIVITY INTELLECTUAL PROPERTY LAW FIRM (CN)
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