Title:
ARYL AND AMINOARYL SUBSTITUTED SEROTONIN RECEPTOR AGONIST AND ANTAGONIST LIGANDS
Document Type and Number:
WIPO Patent Application WO2002059082
Kind Code:
A8
Abstract:
The present invention is directed to certain novel compounds represented by structural Formula (I):or a pharmaceutically acceptable salt thereof, wherein Sand Tare described herein. The invention is also concerned with pharmaceutical formulations comprising these novel compounds as active ingredients and the use of the novel compounds and their formulations in the treatment of certain disorders. The compounds of this invention are serotonin agonists and antagonists and are useful in the control or prevention of central nervous system disorders including obesity, anxiety, depression, psychosis, schizophrenia, sleep and sexual disorders, migraine and other conditions associated with cephalic pain, social phobias, and gastrointestinal disorders such as dysfunction of the gastrointestinal tract motility.
Inventors:
ROBICHAUD ALBERT
MITCHELL IAN S
MITCHELL IAN S
Application Number:
PCT/US2001/049373
Publication Date:
February 13, 2003
Filing Date:
December 19, 2001
Export Citation:
Assignee:
BRISTOL MYERS SQUIBB PHARMA CO (US)
International Classes:
A61K31/343; A61K31/4035; A61K31/404; A61K31/407; A61K31/416; A61K31/437; A61K31/473; A61K31/4985; A61K31/55; A61P1/06; A61P3/04; A61P15/00; A61P25/06; A61P25/24; A61P25/28; A61P43/00; C07D209/04; C07D209/08; C07D209/14; C07D209/62; C07D221/10; C07D231/54; C07D231/56; C07D307/85; C07D471/04; C07D487/04; (IPC1-7): C07D231/56; A61K31/395; A61P25/00; C07D209/08; C07D307/85; C07D221/10; C07D471/04
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