UREA DERIVATIVES AS INHIBITORS OF CCR-3 RECEPTOR

Title:

UREA DERIVATIVES AS INHIBITORS OF CCR-3 RECEPTOR

Document Type and Number:

WIPO Patent Application WO2002059081

Kind Code:

A3

Abstract:

Urea and amide derivatives inhibit cell function of the chemokine receptor CCR-3. These compounds offer an effective means for treating a range of diseases thought to be mediated by the CCR-3 receptor. A variety of useful area and amide derivatives can be synthesized using liquid and solid-phase synthesis protocols.

Inventors:

PADIA JANAK (US)
HOCKER MICHAEL (US)
NISHITOBA TSUYOSHI (JP)
OHASHI HIROHI (JP)
SAWA EIJI (JP)

Application Number:

PCT/US2002/002280

Publication Date:

January 09, 2003

Filing Date:

January 28, 2002

Export Citation:

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Assignee:

PADIA JANAK (US)
HOCKER MICHAEL (US)
NISHITOBA TSUYOSHI (JP)
OHASHI HIROHI (JP)
SAWA EIJI (JP)

International Classes:

A61P37/00; C07C233/40; C07C235/34; C07C235/78; C07C275/24; (IPC1-7): C07C275/24; A61K31/165; A61K31/17; A61P37/00; C07C233/40; C07C235/34; C07C235/78; C07C323/62; C07D317/62

Domestic Patent References:

WO2001009088A1	2001-02-08
WO2000053172A1	2000-09-14
WO2000041685A1	2000-07-20

Foreign References:

EP0903349A2

1999-03-24

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