Title:
ARYLAMINO DERIVATIVE ESTROGEN RECEPTOR MODULATOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/284837
Kind Code:
A1
Abstract:
The present invention relates to a compound as represented by formula (I) and a stereoisomer, solvate, deuterated compound or pharmaceutically acceptable salt or pharmaceutical composition thereof, and the use thereof in the preparation of a drug for treating/preventing ER-mediated diseases, wherein each group in formula (I) is as defined in the description.
Inventors:
LI YAO (CN)
WANG WENJING (CN)
SHI ZONGJUN (CN)
SONG CHANGWEI (CN)
REN LEI (CN)
WANG JIE (CN)
TANG PINGMING (CN)
YU YAN (CN)
ZHANG CHEN (CN)
YAN PANGKE (CN)
WANG WENJING (CN)
SHI ZONGJUN (CN)
SONG CHANGWEI (CN)
REN LEI (CN)
WANG JIE (CN)
TANG PINGMING (CN)
YU YAN (CN)
ZHANG CHEN (CN)
YAN PANGKE (CN)
Application Number:
PCT/CN2022/105788
Publication Date:
January 19, 2023
Filing Date:
July 14, 2022
Export Citation:
Assignee:
SICHUAN HAISCO PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D217/14; A61K31/397; A61K31/435; A61K31/437; A61K31/4545; A61P35/00; C07D401/12; C07D401/14; C07D471/04
Domestic Patent References:
| WO2021228210A1 | 2021-11-18 | |||
| WO2019245974A1 | 2019-12-26 | |||
| WO2020037203A2 | 2020-02-20 | |||
| WO2021139756A1 | 2021-07-15 | |||
| WO2019245974A1 | 2019-12-26 | |||
| WO2021228210A1 | 2021-11-18 |
Foreign References:
| CN111825613A | 2020-10-27 | |||
| CN107108611A | 2017-08-29 | |||
| CN109219604A | 2019-01-15 | |||
| US11339162B1 | 2022-05-24 |
Other References:
S. R. SANDLER ET AL.: "Organic Functional Group Preparations", 1983, JOHN WILEY & SONS
H. O. HOUSE: "Modern Synthetic Reactions", 1972, MENLO PARK
T. L. GILCHRIST: "Advanced Organic Chemistry: Reactions, Mechanisms, and Structure", 1992, WILEY-INTERSCIENCE
FUHRHOP, JPENZLIN G: "Organic Synthesis: Concepts, Methods, Starting Materials", 1994, JOHN WILEY & SONS
HOFFMAN, R.V: "Organic Chemistry, An Intermediate Text", 1996, OXFORD UNIVERSITY PRESS
LAROCK, R. C: "Industrial Organic Chemicals: Starting Materials and Intermediates: An Ullmann's Encyclopedia", 1999, JOHN WILEY & SONS
SOLOMONS, T. W. G: "Modern Carbonyl Chemistry", 2000, JOHN WILEY & SONS
STOWELL, J.C.: "Intermediate Organic Chemistry", 1993, WILEY-INTERSCIENCE
"Chemistry of Functional Groups", vol. 73, JOHN WILEY & SONS
H. O. HOUSE: "Modern Synthetic Reactions", 1972, MENLO PARK
T. L. GILCHRIST: "Advanced Organic Chemistry: Reactions, Mechanisms, and Structure", 1992, WILEY-INTERSCIENCE
FUHRHOP, JPENZLIN G: "Organic Synthesis: Concepts, Methods, Starting Materials", 1994, JOHN WILEY & SONS
HOFFMAN, R.V: "Organic Chemistry, An Intermediate Text", 1996, OXFORD UNIVERSITY PRESS
LAROCK, R. C: "Industrial Organic Chemicals: Starting Materials and Intermediates: An Ullmann's Encyclopedia", 1999, JOHN WILEY & SONS
SOLOMONS, T. W. G: "Modern Carbonyl Chemistry", 2000, JOHN WILEY & SONS
STOWELL, J.C.: "Intermediate Organic Chemistry", 1993, WILEY-INTERSCIENCE
"Chemistry of Functional Groups", vol. 73, JOHN WILEY & SONS
Attorney, Agent or Firm:
BEIJING SANYOU INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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