Title:
ATOMIZING NOZZLE WITH AUXILIARY HEATING DEVICE SUITABLE FOR USE IN RAPID FREEZING ENVIRONMENT
Document Type and Number:
WIPO Patent Application WO/2021/179536
Kind Code:
A1
Abstract:
An atomizing nozzle with an auxiliary heating device suitable for use in a rapid freezing environment, suitable for freeze-drying preparation of ultra-fine aerosol particles such as a biological sample and a dry powder sample in an ultra-low temperature environment. The atomizing nozzle comprises an air channel connector (1), a nozzle body (2), a liquid channel connector (3), a heating ring (4), a thermal control module (5), a thermal insulation shell (6), a cryogenic tank flange (7), a sprayer (8), and a sealing ring (9). Auxiliary heating and temperature control of the thermal control device enable the nozzle to smoothly achieve atomization in an ultra-low temperature environment, atomize a liquid biological sample into fine droplets, and quickly freeze the droplets to form fine frozen ice crystals in the ultra-low temperature environment formed using liquid nitrogen, and then sublimate the fine frozen ice crystals to prepare dry powder particles.
Inventors:
ZHANG ZHEN (CN)
CHEN JUN (CN)
WANG XUDONG (CN)
WANG FENGSHAN (CN)
CHEN JUN (CN)
WANG XUDONG (CN)
WANG FENGSHAN (CN)
Application Number:
PCT/CN2020/109920
Publication Date:
September 16, 2021
Filing Date:
August 19, 2020
Export Citation:
Assignee:
BEIJING INST CONTROL ENG (CN)
International Classes:
B05B7/10; B01J2/06; B05B1/34; B05B7/06; B05B7/08; F26B5/06
Foreign References:
| CN111250283A | 2020-06-09 | |||
| CN1094660A | 1994-11-09 | |||
| US4893754A | 1990-01-16 | |||
| JP2017064663A | 2017-04-06 | |||
| CN102089607A | 2011-06-08 | |||
| CN205146480U | 2016-04-13 | |||
| DE102006011391A1 | 2007-09-20 | |||
| US20080308245A1 | 2008-12-18 | |||
| EP3330007A1 | 2018-06-06 |
Attorney, Agent or Firm:
PATENT AGENT OF CHINA AEROSPACE TECHNOLOGY (CN)
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