Title:
BEAD COMPLEX FOR DETECTING NUCLEIC ACID MOLECULE IN BIOLOGICAL SAMPLE AND METHOD FOR DETECTING NUCLEIC ACID USING SAME
Document Type and Number:
WIPO Patent Application WO/2023/018232
Kind Code:
A1
Abstract:
The present invention relates to a bead complex for detecting a nucleic acid molecule in a biological sample and a method for detecting a nucleic acid using same, the bead complex, according to one aspect, enabling the effective isolation, extraction, and detection of a target nucleic acid molecule in a biological sample, and, by analyzing whether the target nucleic acid molecule is present in the biological sample, having the effect of enabling enhanced analytical sensitivity.
Inventors:
JEONG YO HAN (KR)
LEE JEONG JU (KR)
PARK SO HYEON (KR)
HWANG KYUNG AH (KR)
AHN JI HOON (KR)
LEE JEONG JU (KR)
PARK SO HYEON (KR)
HWANG KYUNG AH (KR)
AHN JI HOON (KR)
Application Number:
PCT/KR2022/011953
Publication Date:
February 16, 2023
Filing Date:
August 10, 2022
Export Citation:
Assignee:
SML GENETREE CO LTD (KR)
International Classes:
C12Q1/6811; C12Q1/6886; C12Q1/689; C12Q1/70
Foreign References:
| US5512439A | 1996-04-30 | |||
| US20200392005A1 | 2020-12-17 | |||
| US20060002890A1 | 2006-01-05 |
Other References:
HUNG WEI-CHIH, CHERNG JONG-YUH: "Maleimide-Functionalized PEI600 Grafted Polyurethane: Synthesis, Nano-Complex Formation with DNA and Thiol-Conjugation of the Complexes for Dual DNA Transfection", POLYMERS, vol. 7, no. 10, pages 2131 - 2145, XP093034431, DOI: 10.3390/polym7101503
JANISSEN RICHARD, BERGHUIS BOJK A., DULIN DAVID, WINK MAX, VAN LAAR THEO, DEKKER NYNKE H.: "Invincible DNA tethers: covalent DNA anchoring for enhanced temporal and force stability in magnetic tweezers experiments", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, GB, vol. 42, no. 18, 13 October 2014 (2014-10-13), GB , pages e137 - e137, XP093034434, ISSN: 0305-1048, DOI: 10.1093/nar/gku677
ISABEL GESSNER, XIAOJIE YU, CHRISTIAN JüNGST, ANNIKA KLIMPEL, LINGYU WANG, THOMAS FISCHER, INES NEUNDORF, ASTRID C. SCHAUSS, : "Selective Capture and Purification of MicroRNAs and Intracellular Proteins through Antisense-vectorized Magnetic Nanobeads", SCIENTIFIC REPORTS, vol. 9, no. 1, 1 December 2019 (2019-12-01), XP055748898, DOI: 10.1038/s41598-019-39575-7
JANISSEN RICHARD, BERGHUIS BOJK A., DULIN DAVID, WINK MAX, VAN LAAR THEO, DEKKER NYNKE H.: "Invincible DNA tethers: covalent DNA anchoring for enhanced temporal and force stability in magnetic tweezers experiments", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, GB, vol. 42, no. 18, 13 October 2014 (2014-10-13), GB , pages e137 - e137, XP093034434, ISSN: 0305-1048, DOI: 10.1093/nar/gku677
ISABEL GESSNER, XIAOJIE YU, CHRISTIAN JüNGST, ANNIKA KLIMPEL, LINGYU WANG, THOMAS FISCHER, INES NEUNDORF, ASTRID C. SCHAUSS, : "Selective Capture and Purification of MicroRNAs and Intracellular Proteins through Antisense-vectorized Magnetic Nanobeads", SCIENTIFIC REPORTS, vol. 9, no. 1, 1 December 2019 (2019-12-01), XP055748898, DOI: 10.1038/s41598-019-39575-7
Attorney, Agent or Firm:
THEWAVE IP LAW FIRM (KR)
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