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Title:
BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION
Document Type and Number:
WIPO Patent Application WO/2022/047603
Kind Code:
A1
Abstract:
Provided herein are novel β-lactamase inhibitors, for the treatment of bacterial infections in combination with β-lactam antibiotics, including infection caused by drug resistant organisms and especially multi-drug resistant organisms. It includes compounds according to formula (I): or pharmaceutically acceptable salts thereof, wherein M and R are as defined herein.

Inventors:
YANG ZHIXIANG (CN)
YANG HAIKANG (CN)
JI JINBO (CN)
GAO YUANYU (CN)
TANG DONG (CN)
ZHAI LIJUAN (CN)
IQBAL ZAFAR (CN)
SUN JIAN (CN)
JI JINGWEN (CN)
MU YANGXIU (CN)
HE LILI (CN)
LIU YUANBAI (CN)
MA XUEQIN (CN)
YU JIANQIANG (CN)
Application Number:
PCT/CN2020/112758
Publication Date:
March 10, 2022
Filing Date:
September 01, 2020
Export Citation:
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Assignee:
NINGXIA ACADEMY AGRICULTURE & FORESTRY SCIENCES (CN)
International Classes:
C07D471/08; A61K31/439; A61P31/04
Domestic Patent References:
WO2016116788A12016-07-28
WO2003063864A22003-08-07
WO2017045510A12017-03-23
WO2015110966A12015-07-30
WO2014141132A12014-09-18
WO2015150926A12015-10-08
WO2013030733A12013-03-07
Other References:
See also references of EP 4146650A4
Attorney, Agent or Firm:
CHINA SINDA INTELLECTUAL PROPERTY LIMITED (CN)
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