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Title:
BICYCLIC COMPOUND
Document Type and Number:
WIPO Patent Application WO/2010/050445
Kind Code:
A1
Abstract:
A compound having an ACC inhibitory effect and useful for prevention/treatment of adiposis, diabetes, hypertension, hyperlipemia, heart failure, diabetic complication, metabolic syndrome, sarcopenia, cancer and the like.  The compound has excellent medicinal effects. Specifically disclosed is a compound represented by formula (I) (wherein the symbols are as defined in the description) or a salt thereof.

Inventors:
KAMATA MAKOTO (JP)
YAMASHITA TOHRU (JP)
KINA ASATO (JP)
AMANO MICHIKO (JP)
Application Number:
PCT/JP2009/068356
Publication Date:
May 06, 2010
Filing Date:
October 26, 2009
Export Citation:
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Assignee:
TAKEDA PHARMACEUTICAL (JP)
KAMATA MAKOTO (JP)
YAMASHITA TOHRU (JP)
KINA ASATO (JP)
AMANO MICHIKO (JP)
International Classes:
C07D235/14; A61K31/343; A61K31/381; A61K31/4155; A61K31/4184; A61K31/42; A61K31/422; A61K31/423; A61K31/427; A61K31/428; A61K31/433; A61K31/4355; A61K31/437; A61K31/443; A61P3/04; A61P3/06; A61P3/10; A61P9/04; A61P9/12; A61P21/00; A61P35/00; A61P43/00; C07D261/20; C07D263/56; C07D277/64; C07D307/81; C07D333/58; C07D405/12; C07D407/12; C07D413/12; C07D417/12; C07D471/04; C07D491/048
Domestic Patent References:
WO2004021984A22004-03-18
WO2000054729A22000-09-21
WO1995009159A11995-04-06
WO2003045925A12003-06-05
WO2007013691A12007-02-01
WO2007119833A12007-10-25
WO2008090944A12008-07-31
WO2008102749A12008-08-28
WO2007013694A12007-02-01
WO2007018314A22007-02-15
WO2008093639A12008-08-07
WO2008099794A12008-08-21
WO2004041266A12004-05-21
WO2004106276A12004-12-09
WO2005063729A12005-07-14
WO2005063725A12005-07-14
WO2005087710A12005-09-22
WO2005095338A12005-10-13
WO2007013689A12007-02-01
WO2008001931A22008-01-03
WO2006112549A12006-10-26
WO2007028135A22007-03-08
WO2008047821A12008-04-24
WO2008050821A12008-05-02
WO2008136428A12008-11-13
WO2008156757A12008-12-24
WO2001014372A22001-03-01
WO2004039365A12004-05-13
WO1997010224A11997-03-20
WO2001082925A12001-11-08
WO2001087834A12001-11-22
WO2002006234A12002-01-24
WO2004048363A12004-06-10
WO2005030740A12005-04-07
WO2005058823A12005-06-30
WO2005113504A12005-12-01
Foreign References:
JP2006502162A2006-01-19
JP2005194191A2005-07-21
JPS63264456A1988-11-01
JPH07224063A1995-08-22
JPH09235278A1997-09-09
JP2006131559A2006-05-25
US4808595A1989-02-28
US6355660B12002-03-12
US20040087600A12004-05-06
EP1179532A12002-02-13
Other References:
See also references of EP 2351743A4
TETRAHEDRON LETTERS, vol. 48, no. 15, 2007, pages 2661 - 2665
"Design of Molecules", vol. 7, 1990, HIROKAWA SHOTEN, article "IYAKUHIN no KAIHATSU", pages: 163 - 198
"ORGANIC FUNCTIONAL GROUP PREPARATIONS", 1989, ACADEMIC PRESS, INC.
"Comprehensive Organic Transformations", 1989, VCH PUBLISHERS INC.
BIOORGANIC MEDICINAL CHEMISTRY LETTERS, 2007, pages 3630 - 3635
JOURNAL OF CHEMICAL SOCIETY, 1937, pages 1530 - 1534
TETRAHEDRON LETTERS, 1980, pages 769 - 770
JOURNAL OF MEDICINAL CHEMISTRY, 1998, pages 2439 - 2441
"Jikken Kagaku Kouza", vol. 20, THE CHEMICAL SOCIETY OF JAPAN, pages: 304,477 - 479
"Protective Groups in Organic Synthesis", 1980, JOHN WILEY AND SONS
JOURNAL OF MEDICINAL CHEMISTRY, 1998, pages 2146 - 2163
SYNLETT, 2005, pages 2130 - 2134
JOURNAL OF MEDICINAL CHEMISTRY, 1994, pages 3108 - 3120
PHOTOCHEMISTRY, 1971, pages 539 - 544
JOURNAL OF ORGANIC CHEMISTRY, 2005, pages 2494 - 2502
TETRAHEDRON, 1990, pages 5177 - 5186
ORGANIC LETTERS, 2006, pages 5661 - 5664
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 1999, pages 2609 - 2622
TETRAHEDRON LETTERS, 1994, pages 3309 - 3312
BIOORGANIC AND MEDICINAL CHEMISTRY, 1999, pages 2945 - 2952
JOURNAL OF ORGANIC CHEMISTRY, 1992, pages 1663 - 1671
JOURNAL OF ORGANIC CHEMISTRY, 1993, pages 5886 - 5888
JOURNAL OF ORGANIC CHEMISTRY, 1990, pages 4892 - 4897
TETRAHEDRON, 1990, pages 7663 - 7666
SYNLETT, 2006, pages 1255 - 1259
TETRAHEDRON, 2005, pages 5253 - 5260
JOURNAL OF AMERICAN CHEMICAL SOCIETY, 1938, pages 2084 - 2085
JOURNAL OF ORGANIC CHEMISTRY, 2003, pages 5758 - 5761
BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, 2005, pages 2998 - 3001
TETRAHEDRON: ASYMMETRY, 1994, pages 1793 - 1804
TETRAHEDRON: ASYMMETRY, 2003, pages 689 - 692
JOURNAL OF ORGANIC CHEMISTRY, 1997, pages 261 - 274
TETRAHEDRON LETTERS, 1989, pages 2581 - 2584
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 1992, pages 7 - 18
JOURNAL OF MEDICINAL CHEMISTRY, 2006, pages 5282 - 5290
JOURNAL OF MEDICINAL CHEMISTRY, 1993, pages 2703 - 2705
BULLETIN OF CHEMICAL SOCIETY JAPAN, 1983, pages 2762 - 2767
JOURNAL OF HETEROCYCLIC CHEMISTRY, 1996, pages 1051 - 1056
JOURNAL OF AMERICAN CHEMICAL SOCIETY, 1954, pages 1286 - 1289
JOURNAL OF MEDICINAL CHEMISTRY, 2006, pages 8378 - 8383
SYNLETT, 2006, pages 1908 - 1912
RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 1998, pages 542 - 547
JOURNAL OF HETEROCYCLIC CHEMISTRY, 1989, pages 281 - 284
JOURNAL OF HETEROCYCLIC CHEMISTRY, 1971, pages 57 - 60
JOURNAL OF MEDICINAL CHEMISTRY, 2000, pages 1293 - 1310
SYNTHESIS, 1986, pages 749 - 751
JOURNAL OF AMERICAN CHEMICAL SOCIETY, 1984, pages 158 - 163
BIOORGANIC AND MEDICINAL CHEMICAL LETTERS, 2007, pages 1803 - 1807
JOURNAL OF CHEMICAL SOCIETY, 1959, pages 3362 - 3369
JOURNAL OF MEDICINAL CHEMISTRY, 1997, pages 2085 - 2101
JOURNAL OF FLUORINE CHEMISTRY, 2001, pages 135 - 146
JOURNAL OF ORGANIC CHEMISTRY, 1992, pages 565 - 573
SYNTHETIC COMMUNICATIONS, 1981, pages 969 - 978
JOURNAL OF MEDICINAL CHEMISTRY, 1978, pages 1158 - 1162
SYNTHETIC COMMUNICATIONS, 2003, pages 3435 - 3454
JOURNAL OF AMERICAN CHEMICAL SOCIETY, 2005, pages 2844 - 2845
Attorney, Agent or Firm:
TAKASHIMA, HAJIME (JP)
Takashima 1 (JP)
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