Title:
BICYCLIC DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE
Document Type and Number:
WIPO Patent Application WO/2003/045929
Kind Code:
A1
Abstract:
A heterocyclic compound represented by the general formula (V) (wherein R1b represents substituted C6-10 aryl, etc.; Ta represents a single bond, C1-6 alkyl, -CH2O-, etc.; X and Y are the same or different and each represents optionally substituted nitrogen, etc.; the broken lines each indicates a single bond or double bond; Za represents nitrogen or CH; W represents a single bond, oxygen, etc.; and Q represents an optionally substituted C6-10 aryl or optionally substituted aromatic heterocyclic group) or a salt of the compound. The compound and salt have excellent tyrosin kinase inhibitory activity. Also provided is a medicinal composition containing the heterocyclic compound or salt.
More Like This:
| JPWO2010087315 | Anti-Alzheimer's disease agent |
| JP6359234 | Sustained release formulation composition for animals |
| WO/2003/048109 | NOVEL GLUCAGON ANTAGONISTS |
Inventors:
ODA TSUNEO (JP)
IMADA TAKASHI (JP)
NAITO KENICHIRO (JP)
TAMURA TOSHIYA (JP)
FURUYA SHUICHI (JP)
IMADA TAKASHI (JP)
NAITO KENICHIRO (JP)
TAMURA TOSHIYA (JP)
FURUYA SHUICHI (JP)
Application Number:
PCT/JP2002/012264
Publication Date:
June 05, 2003
Filing Date:
November 25, 2002
Export Citation:
Assignee:
TAKEDA CHEMICAL INDUSTRIES LTD (JP)
ODA TSUNEO (JP)
IMADA TAKASHI (JP)
NAITO KENICHIRO (JP)
TAMURA TOSHIYA (JP)
FURUYA SHUICHI (JP)
ODA TSUNEO (JP)
IMADA TAKASHI (JP)
NAITO KENICHIRO (JP)
TAMURA TOSHIYA (JP)
FURUYA SHUICHI (JP)
International Classes:
A61K31/423; A61K31/437; A61K31/5377; A61P35/00; A61P43/00; C07D235/10; C07D263/56; C07D263/57; C07D413/04; C07D413/12; C07D413/14; C07D471/04; (IPC1-7): C07D263/56; A61K31/423; A61K31/437; A61K31/5377; A61K38/05; A61P35/00; A61P43/00; C07D413/04; C07D471/04
Domestic Patent References:
| WO1998003505A2 | 1998-01-29 | |||
| WO1996011917A1 | 1996-04-25 | |||
| WO2002036580A2 | 2002-05-10 |
Foreign References:
| GB1388102A | 1975-03-19 | |||
| GB2008108A | 1979-05-31 |
Other References:
SODERLIND KRISTA-JUNE ET AL.: "Bis-benzimidazole anticancer agents: targeting human tumour helicases", ANTI-CANCER DRUG DESIGN, vol. 14, no. 1, 1999, pages 19 - 36, XP000984519
DOW R.L. ET AL.: "Benzyloxazolidine-2,4-diones as potent hypoglycemic agents", J. MED. CHEM., vol. 34, no. 5, 1991, pages 1538 - 1544, XP002093529
See also references of EP 1460067A4
DOW R.L. ET AL.: "Benzyloxazolidine-2,4-diones as potent hypoglycemic agents", J. MED. CHEM., vol. 34, no. 5, 1991, pages 1538 - 1544, XP002093529
See also references of EP 1460067A4
Attorney, Agent or Firm:
Takahashi, Shuichi c/o Osaka Plant of TAKEDA CHEMICAL INDUSTRIES LTD. (17-85, Jusohonmachi 2-chome, Yodogawa-k, Osaka-shi Osaka, JP)
Download PDF:
Previous Patent: 5-SULPHANYL-4H-1,2,4-TRIAZOLE DERIVATIVES AND THEIR USE AS MEDICINE
Next Patent: METHOD OF CONVERTING CUMENE HYDROPEROXIDE
Next Patent: METHOD OF CONVERTING CUMENE HYDROPEROXIDE