Title:
BIFUNCTIONAL COMPOUNDS FOR DEGRADING ITK VIA UBIQUITIN PROTEOSOME PATHWAY
Document Type and Number:
WIPO Patent Application WO/2023/069514
Kind Code:
A9
Abstract:
This disclosure relates to compounds of formulae I, II and III useful for degrading ITK via a ubiquitin proteolytic pathway. This disclosure also provides pharmaceutically acceptable compositions comprising said compounds, and methods of using the compositions in the treatment of various diseases, conditions, and/or disorders.
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Inventors:
OZBOYA KAREM (US)
MENG YAN (US)
KATO DAISUKE (US)
KEENAN KATHERINE (US)
PENG GE (US)
ROBBINS DANIEL W (US)
MENG YAN (US)
KATO DAISUKE (US)
KEENAN KATHERINE (US)
PENG GE (US)
ROBBINS DANIEL W (US)
Application Number:
PCT/US2022/047129
Publication Date:
August 03, 2023
Filing Date:
October 19, 2022
Export Citation:
Assignee:
NURIX THERAPEUTICS INC (US)
OZBOYA KAREM (US)
MENG YAN (US)
OZBOYA KAREM (US)
MENG YAN (US)
International Classes:
C07D403/14; A61P29/00; A61P35/00; A61P37/00; C07D413/14; C07D417/14
Attorney, Agent or Firm:
NOSON, Kevin et al. (US)
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