Title:
BIOMIMETIC MEMBRANE STRUCTURE BASED ON ZINC PROTOPORPHYRIN ORGANIC CAGE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/155453
Kind Code:
A1
Abstract:
A biomimetic membrane structure based on a zinc protoporphyrin organic cage and a use thereof. The zinc protoporphyrin organic cage is prepared by enabling a tetraaldehyde phenyl porphyrin and (2,4,6-tri-butoxybenzene-1,3,5-tri)trimethylamine chloroform solution and a zinc acetate methanol solution to undergo a reaction; a zinc protoporphyrin organic cage, phospholipid and cholesterol chloroform solution of a certain concentration is added dropwise to the surface of an electrode, and a solvent is fully volatilized to obtain the biomimetic membrane structure. The calculated light-emitting intensity is associated with the concentration of a light-emitting body and membrane solution to obtain an optimal light-emitting condition. An electrochemical luminescence device is simple, the operation is simple and convenient, and a change trend of the light intensity along with the concentration of a reactant can be conveniently detected; by means of electrochemiluminescence detection, an initial reaction condition, a speed and a path can be controlled by adjusting the potential, so as to conveniently perform in-situ and on-site analysis; the present invention is applicable to melittin detection.
Inventors:
DENG SHENGYUAN (CN)
WAN YING (CN)
MAN TIANTIAN (CN)
PIAO YUHAO (CN)
CHEN JIALIANG (CN)
ZHAO YUANZHANG (CN)
FENG XUYU (CN)
HUANG YAQI (CN)
XIAO MING (CN)
WAN YING (CN)
MAN TIANTIAN (CN)
PIAO YUHAO (CN)
CHEN JIALIANG (CN)
ZHAO YUANZHANG (CN)
FENG XUYU (CN)
HUANG YAQI (CN)
XIAO MING (CN)
Application Number:
PCT/CN2022/125334
Publication Date:
August 24, 2023
Filing Date:
October 14, 2022
Export Citation:
Assignee:
UNIV NANJING SCI & TECH (CN)
International Classes:
C09K11/02; G01N27/416; G01N27/30; G01N27/327
Foreign References:
| CN114705742A | 2022-07-05 | |||
| CN113429430A | 2021-09-24 | |||
| CN102573914A | 2012-07-11 | |||
| CN108827817A | 2018-11-16 | |||
| CN105092564A | 2015-11-25 | |||
| CN112730386A | 2021-04-30 | |||
| EP0745843A2 | 1996-12-04 | |||
| JP2009192235A | 2009-08-27 |
Attorney, Agent or Firm:
HANGZHOU QIUSHI PATENT OFFICE CO..LTD. (CN)
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