Title:
CANCER DIAGNOSTIC MARKER USING TRANSPOSASE-ACCESSIBLE CHROMATIN SEQUENCING INFORMATION ABOUT INDIVIDUAL, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/204297
Kind Code:
A1
Abstract:
The present invention relates to a cancer diagnostic marker using transposase-accessible chromatin using sequencing (ATAC sequencing), and a use thereof. An open chromatin structural variation marker according to the present invention enables the identification of structural variations of chromatin with high accuracy so as to be useful as a cancer diagnostic marker, and can be used as a new cancer diagnostic marker when detecting chromatin structural variations by using a composition for detecting the marker.
Inventors:
LEE DAEYOUP (KR)
KIM TAEMOOK (KR)
HAN SUNGWOOK (KR)
KIM TAEMOOK (KR)
HAN SUNGWOOK (KR)
Application Number:
PCT/KR2019/015856
Publication Date:
October 08, 2020
Filing Date:
November 19, 2019
Export Citation:
Assignee:
KOREA ADVANCED INST SCI & TECH (KR)
International Classes:
G01N33/574; G16B20/00; G16B30/10; G16H50/20; G16H50/70
Domestic Patent References:
| WO2007078599A2 | 2007-07-12 |
Foreign References:
| KR20190024253A | 2019-03-08 | |||
| US20160060691A1 | 2016-03-03 |
Other References:
CORCES, M. R.: "The chromatin accessibility landscape of primary human cancers", SCIENCE, vol. 362, 26 October 2018 (2018-10-26), pages 1 - 13, XP055723802
CHEN, H.: "New insights on human essential genes based on integrated analysis", BIORXIV, 10 October 2018 (2018-10-10), pages 1 - 30, XP055747208
CHEN, H.: "New insights on human essential genes based on integrated analysis", BIORXIV, 10 October 2018 (2018-10-10), pages 1 - 30, XP055747208
Attorney, Agent or Firm:
LEE, Cheo Young et al. (KR)
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