Title:
CANCER EVALUATION METHOD AND CANCER EVALUATION SYSTEM
Document Type and Number:
WIPO Patent Application WO/2016/042805
Kind Code:
A1
Abstract:
Provided is a cancer evaluation method which enables the highly accurate estimation of the risk of suffering from cancer in a subject, does not have disadvantages of early degeneration and high cost which are normally associated with a method utilizing an amino acid concentration in blood, and can be readily applied to a mass medical examination.
The method comprises: step S1 of measuring the concentrations of elements of interest in a serum sample 2 collected from a subject; step S2 of assigning the data on the measured concentrations of the elements to a predetermined determination function to perform a calculation; and step S3 of determining whether or not any type of cancer is developed in the subject on the basis of the calculation results that are obtained using the data on the concentrations and the determination function. The determination is carried out in accordance with the balance (pattern) of the concentrations of the elements. It is preferred that the elements are 7 elements, i.e., S, P, Mg, Zn, Cu, Ti and Rb, or 16 elements, i.e., Na, Mg, Al, P, K, Ca, Ti, Mn, Fe, Zn, Cu, Se, Rb, Ag, Sn and S.
Inventors:
INAGAKI SEIICHI (JP)
OKAMOTO NAOYUKI (JP)
OKAMOTO NAOYUKI (JP)
Application Number:
PCT/JP2015/057005
Publication Date:
March 24, 2016
Filing Date:
March 10, 2015
Export Citation:
Assignee:
RENATECH CO LTD (JP)
International Classes:
G01N33/84
Foreign References:
| JP2005524071A | 2005-08-11 | |||
| JP2011047715A | 2011-03-10 |
Other References:
HONG-DAR ISAAC WU ET AL.: "Differentiation of serum levels of trace elements in normal and malignant breast patients", BIOLOGICAL TRACE ELEMENT RESEARCH, vol. 113, 2006, pages 9 - 18, XP008185263
HIROFUMI TAKAGI: "Discriminant analysis and multiple logistic model", JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, vol. 174, no. 4, 1995, pages 285 - 289, XP008185288
SANJEEV K. GUPTA ET AL.: "Serum trace elements and Cu/Zn ratio in breast cancer patients", JOURNAL OF SURGICAL ONCOLOGY, vol. 46, no. 3, 1991, pages 178 - 181, XP055393817
CHAO TAN ET AL.: "Early prediction of lung cancer based on the combination of trace element analysis in urine and an Adaboost algorithm", JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, vol. 49, no. 3, April 2009 (2009-04-01), pages 746 - 752, XP026006079, DOI: doi:10.1016/j.jpba.2008.12.010
See also references of EP 3182132A4
HIROFUMI TAKAGI: "Discriminant analysis and multiple logistic model", JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, vol. 174, no. 4, 1995, pages 285 - 289, XP008185288
SANJEEV K. GUPTA ET AL.: "Serum trace elements and Cu/Zn ratio in breast cancer patients", JOURNAL OF SURGICAL ONCOLOGY, vol. 46, no. 3, 1991, pages 178 - 181, XP055393817
CHAO TAN ET AL.: "Early prediction of lung cancer based on the combination of trace element analysis in urine and an Adaboost algorithm", JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, vol. 49, no. 3, April 2009 (2009-04-01), pages 746 - 752, XP026006079, DOI: doi:10.1016/j.jpba.2008.12.010
See also references of EP 3182132A4
Attorney, Agent or Firm:
IZUMI, Katsufumi (JP)
Spring Katsufumi (JP)
Spring Katsufumi (JP)
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