Title:
CARBONIC ANHYDRASE INHIBITORS
Document Type and Number:
WIPO Patent Application WO/2003/013655
Kind Code:
A2
Abstract:
Methods of treating or preventing carbonic anhydrase associated disorders or diseases in a subject in need of such treatment as prevention comprising the administration of cyclooxygenase -2 inhibitors, or structurally related compounds, having carbonic anhydrase inhibitory properties, as well as combinations of the cyclooxygenase -2 inhibitors, or structurally related compounds, with anti- inflammatory agents or drugs, antineoplastic agents or drugs or ophthalmic agents or drugs in methods of treatment and prevention of disorders or diseases.
Inventors:
O'NEAL JANET M (US)
MASFERRER JAIME L (US)
MASFERRER JAIME L (US)
Application Number:
PCT/US2002/025447
Publication Date:
February 20, 2003
Filing Date:
August 09, 2002
Export Citation:
Assignee:
PHARMACIA CORP (US)
O'NEAL JANET M (US)
MASFERRER JAIME L (US)
O'NEAL JANET M (US)
MASFERRER JAIME L (US)
International Classes:
C07D231/12; A61K31/18; A61K31/415; A61K31/4188; A61K31/42; A61K31/4965; A61K31/513; A61K31/635; A61K45/00; A61K45/06; A61P3/12; A61P7/00; A61P7/10; A61P11/00; A61P21/00; A61P25/00; A61P25/02; A61P25/08; A61P27/02; A61P27/06; A61P35/00; A61P35/02; A61P43/00; C07D261/08; C07D495/04; (IPC1-7): A61P3/12; A61K31/18; A61K31/415; A61K31/4188; A61K31/42; A61K31/635; A61K45/06; A61P7/10; A61P21/00; A61P25/08; A61P27/02; A61P27/06; A61P35/00; A61P35/02; A61P43/00
Domestic Patent References:
| WO2001028548A1 | 2001-04-26 | |||
| WO1997038986A1 | 1997-10-23 |
Foreign References:
| US5760068A | 1998-06-02 | |||
| EP0826676A1 | 1998-03-04 | |||
| US5944021A | 1999-08-31 |
Other References:
GR]NEBERG, S. ET AL.,: "Subnanomolar Inhibitors from Computer Screening: A Model Study Using Human Carbonic Anhydrase II." ANGEW. CHEM. INT. ED., vol. 40, no. 2, - 2001 pages 389-393, XP001126207
Attorney, Agent or Firm:
Doty, Kathryn J. (Powers Leavitt & Roedel, 16th Floor, One
Metropolitan Squar, St. Louis MO, US)
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