Title:
CELL CULTURING MEMBER, AND METHOD FOR MODIFYING SURFACE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/138799
Kind Code:
A1
Abstract:
Provided are: a cell culturing member which has excellent cell culturing performance and has long-term stability of the cell culturing performance; and a method for modifying the surface of the cell culturing member. The cell culturing member according to the present invention is one in which at least an adhesive cell holding region comprises a polymeric compound, the cell culturing member being characterized in that at least a portion of the holding region is a surface modified region in which a fluorine atom is chemically bound directly to each of some of carbon atoms and/or silicon atoms constituting the polymeric compound. It becomes possible to provide a cell culturing member in which the adhesiveness of adhesive cells to the surface modified region is improved, the deterioration in this adhesiveness over time is prevented, and cell culturing performance and the long-term stability of the cell culturing performance are excellent.
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Inventors:
SAITO NAOTO (JP)
UEMURA TAKESHI (JP)
HISANO KAZUTOSHI (JP)
SATO YOSHINORI (JP)
YAMAMOTO MASASHI (JP)
NII KEIICHI (JP)
NISHIDA TETSUO (JP)
UEMURA TAKESHI (JP)
HISANO KAZUTOSHI (JP)
SATO YOSHINORI (JP)
YAMAMOTO MASASHI (JP)
NII KEIICHI (JP)
NISHIDA TETSUO (JP)
Application Number:
PCT/JP2021/047797
Publication Date:
June 30, 2022
Filing Date:
December 23, 2021
Export Citation:
Assignee:
UNIV SHINSHU (JP)
STELLA CHEMIFA CORP (JP)
STELLA CHEMIFA CORP (JP)
International Classes:
C12M3/00; C08J7/12
Foreign References:
| JPH04330277A | 1992-11-18 | |||
| JP2005218444A | 2005-08-18 | |||
| JP2010150460A | 2010-07-08 | |||
| JP2014515692A | 2014-07-03 |
Other References:
SCHROEPFER MICHAELA, JUNGHANS FRAUKE, VOIGT DIANA, MEYER MICHAEL, BREIER ANETTE, SCHULZE-TANZIL GUNDULA, PRADE INA: "Gas-Phase Fluorination on PLA Improves Cell Adhesion and Spreading", ACS OMEGA, vol. 5, no. 10, 17 March 2020 (2020-03-17), US , pages 5498 - 5507, XP055945398, ISSN: 2470-1343, DOI: 10.1021/acsomega.0c00126
TAKENAKA, ASAO : "Proposal of "novel macromolecular carrier" based on COF coupling technology involving fluorine gas treatment", SEPARATION PROCESS ENGINEERING, vol. 48, no. 1, 1 January 2018 (2018-01-01), Japan , pages 63 - 66, XP009537760, ISSN: 1343-7860
TAKENAKA, ASAO : "Proposal of "novel macromolecular carrier" based on COF coupling technology involving fluorine gas treatment", SEPARATION PROCESS ENGINEERING, vol. 48, no. 1, 1 January 2018 (2018-01-01), Japan , pages 63 - 66, XP009537760, ISSN: 1343-7860
Attorney, Agent or Firm:
KOYAMA Yasushi (JP)
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