Title:
CELL MICROSHEET PREPARATION DEVICE, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/103322
Kind Code:
A1
Abstract:
A cell microsheet preparation device, and a preparation method therefor and the use thereof, wherein the cell microsheet preparation device comprises a base material for culturing cells, the base material is modified with a temperature-sensitive polymer, the temperature-sensitive polymer is modified with an anti-cell-adhesion agent as an isolation strip in a patterned manner, and the surface of the base material modified with the temperature-sensitive polymer is set to be divided into a number of mutually independent areas.
Inventors:
ZHANG ZHIYONG (CN)
WANG WENHAO (CN)
SONG LIZHI (CN)
WANG WENHAO (CN)
SONG LIZHI (CN)
Application Number:
PCT/CN2022/098968
Publication Date:
June 15, 2023
Filing Date:
June 15, 2022
Export Citation:
Assignee:
GUANGDONG REGEN MED SCIENCE AND TECH LTD (CN)
International Classes:
C12M3/04; C12M3/00
Foreign References:
| CN108164656A | 2018-06-15 | |||
| CN103649305A | 2014-03-19 | |||
| JP2014103857A | 2014-06-09 | |||
| JP2013099272A | 2013-05-23 |
Other References:
KUMASHIRO YOSHIKAZU, MATSUNAGA TERUYUKI, MURAOKA MEGUMI, TANAKA NOBUYUKI, ITOGA KAZUYOSHI, KOBAYASHI JUN, TOMIYAMA YUMIKO, KURODA : "Rate control of cell sheet recovery by incorporating hydrophilic pattern in thermoresponsive cell culture dish : Rate Control of Cell Sheet Recovery by Incorporating Hydrophilic Pattern", JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, JOHN WILEY & SONS, US, vol. 102, no. 8, 1 August 2014 (2014-08-01), US , pages 2849 - 2856, XP093070538, ISSN: 1549-3296, DOI: 10.1002/jbm.a.34959
XIA YONGQING, TANG YING, WU HAN, ZHANG JING, LI ZONGYI, PAN FANG, WANG SHENGJIE, WANG XIAOJUAN, XU HAI, LU JIAN REN: "Fabrication of Patterned Thermoresponsive Microgel Strips on Cell-Adherent Background and Their Application for Cell Sheet Recovery", APPLIED MATERIALS & INTERFACES, AMERICAN CHEMICAL SOCIETY, US, vol. 9, no. 2, 18 January 2017 (2017-01-18), US , pages 1255 - 1262, XP093070541, ISSN: 1944-8244, DOI: 10.1021/acsami.6b12762
XIA YONGQING, TANG YING, WU HAN, ZHANG JING, LI ZONGYI, PAN FANG, WANG SHENGJIE, WANG XIAOJUAN, XU HAI, LU JIAN REN: "Fabrication of Patterned Thermoresponsive Microgel Strips on Cell-Adherent Background and Their Application for Cell Sheet Recovery", APPLIED MATERIALS & INTERFACES, AMERICAN CHEMICAL SOCIETY, US, vol. 9, no. 2, 18 January 2017 (2017-01-18), US , pages 1255 - 1262, XP093070541, ISSN: 1944-8244, DOI: 10.1021/acsami.6b12762
Attorney, Agent or Firm:
SHENZHEN CENFO INNOVATIVE INTELLECTUAL PROPERTY CO., LTD. (CN)
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