Title:
CHIMERIC ANTIGEN RECEPTOR MACROPHAGE, METHOD FOR PREPARING SAME, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/246003
Kind Code:
A1
Abstract:
Provided are a chimeric antigen receptor macrophage, a method for preparing same, and use thereof. The chimeric antigen receptor macrophage is a mouse bone marrow-derived macrophage comprising a chimeric antigen receptor modification and expressing the chimeric antigen receptor.
Inventors:
WAN XIAOCHUN (CN)
CHEN YOUHAI (CN)
LIU MAOXUAN (CN)
DAI KUN (CN)
LIU JUNCHEN (CN)
CHEN YOUHAI (CN)
LIU MAOXUAN (CN)
DAI KUN (CN)
LIU JUNCHEN (CN)
Application Number:
PCT/CN2022/137819
Publication Date:
December 28, 2023
Filing Date:
December 09, 2022
Export Citation:
Assignee:
SHENZHEN INST ADV TECH (CN)
International Classes:
C12N5/10; C12N15/867; C12Q1/02
Domestic Patent References:
| WO2021147928A1 | 2021-07-29 | |||
| WO2021223376A1 | 2021-11-11 |
Foreign References:
| CN115011561A | 2022-09-06 | |||
| CN113980965A | 2022-01-28 | |||
| CN111057719A | 2020-04-24 | |||
| US20200297763A1 | 2020-09-24 |
Other References:
JIN CHEN, ZHANG CAI: "Chimeric antigen receptor-modified immune cells and their application in tumor immunotherapy", CHINESE JOURNAL OF CANCER BIOTHERAPY, vol. 28, no. 6, 25 June 2021 (2021-06-25), pages 549 - 557, XP093121022
PAN KEVIN, FARRUKH HIZRA, CHITTEPU VEERA CHANDRA SEKHAR REDDY, XU HUIHONG, PAN CHONG-XIAN, ZHU ZHENG: "CAR race to cancer immunotherapy: from CAR T, CAR NK to CAR macrophage therapy", JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, BIOMED CENTRAL LTD, LONDON UK, vol. 41, no. 1, 31 March 2022 (2022-03-31), London UK , pages 119, XP093121023, ISSN: 1756-9966, DOI: 10.1186/s13046-022-02327-z
PAN KEVIN, FARRUKH HIZRA, CHITTEPU VEERA CHANDRA SEKHAR REDDY, XU HUIHONG, PAN CHONG-XIAN, ZHU ZHENG: "CAR race to cancer immunotherapy: from CAR T, CAR NK to CAR macrophage therapy", JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, BIOMED CENTRAL LTD, LONDON UK, vol. 41, no. 1, 31 March 2022 (2022-03-31), London UK , pages 119, XP093121023, ISSN: 1756-9966, DOI: 10.1186/s13046-022-02327-z
Attorney, Agent or Firm:
BEIJING ZHONG XUN TONG DA INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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