Title:
CHONDROITIN SULFATE BIOLOGICAL POLYAMINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/221977
Kind Code:
A1
Abstract:
Disclosed in the present invention are a chondroitin sulfate biological polyamine compound, a preparation method therefor and use thereof. The present invention provides a chondroitin sulfate biological polyamine compound, which is a compound of chondroitin sulfate and biological polyamine. The chondroitin sulfate is non-covalently linked to the biological polyamine, and the biological polyamine comprises one, two, three or more of combinations of spermine, spermidine, putrescine and cadaverine. The chondroitin sulfate biological polyamine compound provided by the present invention has the anti-inflammatory activity remarkably superior to that of common chondroitin sulfate sodium, can be used in the prevention and treatment of inflammatory diseases, especially arthritis and joint damage, as well as the repair of bone tissues, and has the effects of reducing blood fat, resisting oxidation, slowing down aging, prolonging life span and the like.
Inventors:
ZHU XIAOFENG (CN)
ZHAO YUXIANG (CN)
GAO FANBO (CN)
SONG FENGJIE (CN)
MA CHENYANG (CN)
ZHU XINGYU (CN)
ZHAO YUXIANG (CN)
GAO FANBO (CN)
SONG FENGJIE (CN)
MA CHENYANG (CN)
ZHU XINGYU (CN)
Application Number:
PCT/CN2023/094524
Publication Date:
November 23, 2023
Filing Date:
May 16, 2023
Export Citation:
Assignee:
ZHU XIAOFENG (CN)
International Classes:
A61K47/18; A61K31/737; A61P3/06; A61P19/02; A61P29/00; A61P39/06; A61P43/00
Foreign References:
| US20160101067A1 | 2016-04-14 | |||
| US20130310462A1 | 2013-11-21 | |||
| US20110256059A1 | 2011-10-20 | |||
| US20160317702A1 | 2016-11-03 |
Other References:
LIU WU: "Research progress on the pharmacological effects of chondroitin sulfate", CHINA PHARMACEUTICALS., vol. 17, no. 8, 1 January 2008 (2008-01-01), pages 64 - 66, XP093108766
Attorney, Agent or Firm:
LINDA LIU & PARTNERS (CN)
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