Title:
CHONDROITIN SULFATE POLYSACCHARIDE, AND SEMI-SYNTHETIC PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/177749
Kind Code:
A1
Abstract:
The present invention relates to the technical field of medicine, in particular to a chondroitin sulfate polysaccharide, and a semi-synthetic preparation method therefor and the use thereof. A metal salt of the chondroitin sulfate polysaccharide provided by the present invention has an anti-inflammatory effect, and can be used for preparing a drug against inflammatory diseases. In particular, the metal salt of the chondroitin sulfate polysaccharide provided by the present invention has anti-inflammatory and bone-protecting effects, and can be used for preparing a drug against rheumatoid arthritis and for preparing a drug against osteoarthritis. The present invention provides a method for preparing the metal salt of the chondroitin sulfate polysaccharide, and the metal salt of the chondroitin sulfate polysaccharide with different degrees of sulfation can be obtained by semi-synthetic means in the present invention. The method is simple to operate and suitable for large-scale production.
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Inventors:
ZHAO ZHEHUI (CN)
LEI PINGSHENG (CN)
WU LIANQIU (CN)
YANG SHUANG (CN)
WANG WENJIE (CN)
ZHANG HAIJING (CN)
LI XIANG (CN)
LEI PINGSHENG (CN)
WU LIANQIU (CN)
YANG SHUANG (CN)
WANG WENJIE (CN)
ZHANG HAIJING (CN)
LI XIANG (CN)
Application Number:
PCT/CN2020/078075
Publication Date:
September 10, 2020
Filing Date:
March 05, 2020
Export Citation:
Assignee:
INST MATERIA MEDICA CAMS (CN)
International Classes:
C08B37/08
Domestic Patent References:
| WO2016159296A1 | 2016-10-06 |
Foreign References:
| EP0340628A2 | 1989-11-08 | |||
| US5384398A | 1995-01-24 |
Other References:
See also references of EP 3936527A4
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