Title:
A CLASS OF PYRIMIDINE COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/098821
Kind Code:
A1
Abstract:
Provided are a pyrimidine compound, and a preparation method therefor and the use thereof. Specifically, provided is a compound as represented by formula I or a pharmaceutically acceptable salt thereof. The compound has a new structure, has a good inhibitory effect on EGFRDel19/T790M/C797S mutation, and is expected to treat and/or prevent a variety of diseases mediated by EGFR.
Inventors:
ZHANG QIANG (CN)
WANG JIEGANG (CN)
YE PINGUO (CN)
WANG JIEGANG (CN)
YE PINGUO (CN)
Application Number:
PCT/CN2022/135922
Publication Date:
June 08, 2023
Filing Date:
December 01, 2022
Export Citation:
Assignee:
SHANGHAI ALLIST PHARMACEUTICALS CO LTD (CN)
International Classes:
C07D401/14; A61K31/506; A61P35/00
Domestic Patent References:
| WO2020233669A1 | 2020-11-26 | |||
| WO2020038433A1 | 2020-02-27 | |||
| WO2021180238A1 | 2021-09-16 |
Foreign References:
| CN104761544A | 2015-07-08 | |||
| CN109328059A | 2019-02-12 |
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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