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Title:
COLLAGEN MIMICS
Document Type and Number:
WIPO Patent Application WO2005000872
Kind Code:
A3
Abstract:
A novel collagen mimic comprising a tripeptide unit having the formula (flpYaaGly)n, where flp is 4(S)-fluoro-L-proline, is disclosed. The collagen mimic has increased stability relative to the collagen-related triple helices (ProYaaGly)n, (hypYaaGly)n, and (HypYaaGly)n.

Inventors:
RAINES RONALD T (US)
MITCHELL JULIE C (US)
Application Number:
PCT/US2004/020046
Publication Date:
February 24, 2005
Filing Date:
June 23, 2004
Export Citation:
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Assignee:
WISCONSIN ALUMNI RES FOUND (US)
RAINES RONALD T (US)
MITCHELL JULIE C (US)
International Classes:
A61K38/00; C07K5/08; C07K14/00; C07K14/78; C07K; (IPC1-7): A61K38/00
Foreign References:
US5973112A1999-10-26
US6096710A2000-08-01
US6329506B12001-12-11
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