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Title:
COMBINATION IMMUNOTHERAPY
Document Type and Number:
WIPO Patent Application WO/2023/192639
Kind Code:
A3
Abstract:
In one aspect, methods of treating cancer are provided that comprise: administering to a subject a composition comprising a therapeutically effective amount of: a first agent which inhibits programmed death 1 (PD-1) expression or function, or antagonizes binding to ligands thereof, and a second agent comprising at least one of: a checkpoint antagonist, an IL-7 receptor agonist or soluble IL-7.

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Inventors:
SMITH KELLIE N (US)
PARDOLL DREW M (US)
CAUSHI JUSTINA (US)
ZHANG JIAJIA (US)
Application Number:
PCT/US2023/017196
Publication Date:
November 09, 2023
Filing Date:
March 31, 2023
Export Citation:
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Assignee:
UNIV JOHNS HOPKINS (US)
International Classes:
A61K39/395; A61K45/06; A61P35/00
Domestic Patent References:
WO2020163876A12020-08-13
WO2017177179A12017-10-12
Foreign References:
US20210252122A12021-08-19
Attorney, Agent or Firm:
CORLESS, Peter F. et al. (US)
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