Title:
COMBINATIONAL ANTI-CANCER THERAPY WITH CTLA-4 INHIBITOR AND NON-STEROIDAL ANTI-INFLAMMATORY DRUG
Document Type and Number:
WIPO Patent Application WO/2023/164847
Kind Code:
A1
Abstract:
The present invention provides a combinational anti-cancer therapy with a CTLA-4 inhibitor and a non-steroidal anti-inflammatory drug. Specifically, the present invention provides a product combination comprising: (i) a first pharmaceutical composition, wherein the first pharmaceutical composition comprises (a) a first active ingredient, the first active ingredient being a CTLA-4 inhibitor, and a pharmaceutically acceptable carrier; and (ii) a second pharmaceutical composition, wherein the second pharmaceutical composition comprises (b) a second active ingredient, the second active ingredient being a non-steroidal anti-inflammatory drug, and a pharmaceutically acceptable carrier; wherein, the first pharmaceutical composition and the second pharmaceutical composition are different pharmaceutical compositions or the same pharmaceutical composition. The product combination of the present invention can synergistically treat tumors.
Inventors:
CAI ZELING (CN)
CHEN YI (CN)
ZHANG CHI (CN)
CHEN YI (CN)
ZHANG CHI (CN)
Application Number:
PCT/CN2022/078881
Publication Date:
September 07, 2023
Filing Date:
March 02, 2022
Export Citation:
Assignee:
SHANGHAI CELGEN BIO PHARMACEUTICAL CO LTD (CN)
International Classes:
A61K31/00; A61K39/395; A61P29/00; A61P35/00
Domestic Patent References:
| WO2021205001A1 | 2021-10-14 |
Foreign References:
| US20170136127A1 | 2017-05-18 | |||
| US20190231795A1 | 2019-08-01 | |||
| CN104861067A | 2015-08-26 | |||
| CN108299560A | 2018-07-20 |
Attorney, Agent or Firm:
XU&PARTNERS, LLC. (CN)
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