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Title:
COMPOSITION FOR FLUORESCENT LABELING, FLUORESCENT PROBE, INJECTION AGENT, SYRINGE FILLING, MEDICAL APPARATUS, MEDICAL FIBER MATERIAL, METHOD FOR PRODUCING COMPOSITION FOR FLUORESCENT LABELING, AND METHOD FOR PRODUCING MEDICAL FIBER MATERIAL
Document Type and Number:
WIPO Patent Application WO/2024/043306
Kind Code:
A1
Abstract:
A composition for fluorescent labeling according to the present invention comprises: a compound (A) which is an ICG compound; and a hydroxyl group-containing organic compound (B). This makes it possible to provide, for example, a composition for fluorescent labeling which has excellent compartment identifiability that allows an observation target to be more accurately identified, which has a long light emission time and thus makes it possible to observe the observation target for a long time, and which also reduces a burden on a living body and is excellent in economical efficiency.

Inventors:
TSUCHIDA SHINOBU (JP)
URADE TAKESHI (JP)
Application Number:
PCT/JP2023/030491
Publication Date:
February 29, 2024
Filing Date:
August 24, 2023
Export Citation:
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Assignee:
VITA CORP (JP)
UNIV KOBE NAT UNIV CORP (JP)
International Classes:
C09K11/06; A61K49/00; A61M5/28; A61M37/00
Domestic Patent References:
WO2013109963A12013-07-25
WO2013180127A12013-12-05
Foreign References:
US20170303817A12017-10-26
JP2019522004A2019-08-08
JP2013526297A2013-06-24
Other References:
AKERS W J, BEREZIN M Y, LEE H, ACHILEFU S.: "Predicting in vivo fluorescence lifetime behavior of near-infrared fluorescent contrast agents using in vitro measurements.", JOURNAL OF BIOMEDICAL OPTICS, SPIE, 1000 20TH ST. BELLINGHAM WA 98225-6705 USA, vol. 13, no. 5, 1 September 2008 (2008-09-01), 1000 20th St. Bellingham WA 98225-6705 USA , pages 054042 - 054042-9, XP002754039, ISSN: 1083-3668, DOI: 10.1117/1.2982535
BEREZIN MIKHAIL Y., LEE HYERAN, AKERS WALTER, NIKIFOROVICH GREGORY, ACHILEFU SAMUEL: "Fluorescent lifetime of near infrared dyes for structural analysis of serum albumin", PROCEEDINGS OF SPIE, SPIE, vol. 6867, 7 February 2008 (2008-02-07), pages 68670J, XP093142144, ISSN: 0277-786X, DOI: 10.1117/12.769262
DAS DIPAK KUMAR; MAKHAL KRISHNANDU; SINGHAL SUMIT; GOSWAMI DEBABRATA: "Polarization induced control of multiple fluorescence from a molecule", CHEMICAL PHYSICS LETTERS, ELSEVIER BV, NL, vol. 579, 22 June 2013 (2013-06-22), NL , pages 45 - 50, XP028678565, ISSN: 0009-2614, DOI: 10.1016/j.cplett.2013.06.027
FUYUKI MASANORI: "Multiphoton photodegradation of indocyanine green: Solvent protolysis effect", JOURNAL OF LUMINESCENCE, ELSEVIER BV NORTH-HOLLAND, NL, vol. 170, 23 October 2015 (2015-10-23), NL , pages 97 - 101, XP029328544, ISSN: 0022-2313, DOI: 10.1016/j.jlumin.2015.10.032
Attorney, Agent or Firm:
SANO PATENT OFFICE (JP)
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