Title:
COMPOSITION FOR INHIBITING PLAQUE FORMATION
Document Type and Number:
WIPO Patent Application WO/2022/071457
Kind Code:
A1
Abstract:
Provided is a means for inhibiting plaque formation on the tooth surface and plaque maturation. More specifically, provided is a composition for inhibiting plaque formation which contains a quaternary ammonium salt having a C10-C14 alkyl group and preferably further contains cetylpyridinium chloride.
Inventors:
INUBUSHI JUNYA (JP)
NISHIMURA KEISUKE (JP)
NISHIMURA KEISUKE (JP)
Application Number:
PCT/JP2021/036034
Publication Date:
April 07, 2022
Filing Date:
September 30, 2021
Export Citation:
Assignee:
SUNSTAR SUISSE SA (CH)
INUBUSHI JUNYA (JP)
INUBUSHI JUNYA (JP)
International Classes:
A61K31/14; A61K8/41; A61K8/49; A61K31/4425; A61P1/02; A61P31/04; A61P43/00; A61Q11/00
Foreign References:
| JP2000256155A | 2000-09-19 | |||
| US4022880A | 1977-05-10 | |||
| US4472373A | 1984-09-18 | |||
| JPH1149625A | 1999-02-23 | |||
| JP2005117926A | 2005-05-12 |
Other References:
J.M. TANZER: "In Vitro Evaluation of Seven Cationic Detergents as Antiplaque Agents.", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 15., no. 03., 1 March 1979 (1979-03-01), US , pages 408 - 414., XP002092494, ISSN: 0066-4804
SCHWARZ SOPHIA R.; HIRSCH STEFANIE; HIERGEIST ANDREAS; KIRSCHNECK CHRISTIAN; MUEHLER DENISE; HILLER KARL-ANTON; MAISCH TIM; AL-AHM: "Limited antimicrobial efficacy of oral care antiseptics in microcosm biofilms and phenotypic adaptation of bacteria upon repeated exposure", CLINICAL ORAL INVESTIGATIONS, SPRINGER, BERLIN, DE, vol. 25, no. 5, 8 October 2020 (2020-10-08), DE , pages 2939 - 2950, XP037429972, ISSN: 1432-6981, DOI: 10.1007/s00784-020-03613-w
LIU J.; LING J.-Q.; WU C.D.: "Cetylpyridinium chloride suppresses gene expression associated with halitosis", ARCHIVES OF ORAL BIOLOGY, PERGAMON PRESS, OXFORD., GB, vol. 58, no. 11, 6 September 2013 (2013-09-06), GB , pages 1686 - 1691, XP028734654, ISSN: 0003-9969, DOI: 10.1016/j.archoralbio.2013.08.014
MERCHEL PIOVESAN PEREIRA BEATRIZ, TAGKOPOULOS ILIAS: "Benzalkonium Chlorides: Uses, Regulatory Status, and Microbial Resistance", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 85, no. 13, 1 July 2019 (2019-07-01), US , XP055917898, ISSN: 0099-2240, DOI: 10.1128/AEM.00377-19
J DENT RES, vol. 90, no. 11, 2011, pages 1271 - 1278
SCHWARZ SOPHIA R.; HIRSCH STEFANIE; HIERGEIST ANDREAS; KIRSCHNECK CHRISTIAN; MUEHLER DENISE; HILLER KARL-ANTON; MAISCH TIM; AL-AHM: "Limited antimicrobial efficacy of oral care antiseptics in microcosm biofilms and phenotypic adaptation of bacteria upon repeated exposure", CLINICAL ORAL INVESTIGATIONS, SPRINGER, BERLIN, DE, vol. 25, no. 5, 8 October 2020 (2020-10-08), DE , pages 2939 - 2950, XP037429972, ISSN: 1432-6981, DOI: 10.1007/s00784-020-03613-w
LIU J.; LING J.-Q.; WU C.D.: "Cetylpyridinium chloride suppresses gene expression associated with halitosis", ARCHIVES OF ORAL BIOLOGY, PERGAMON PRESS, OXFORD., GB, vol. 58, no. 11, 6 September 2013 (2013-09-06), GB , pages 1686 - 1691, XP028734654, ISSN: 0003-9969, DOI: 10.1016/j.archoralbio.2013.08.014
MERCHEL PIOVESAN PEREIRA BEATRIZ, TAGKOPOULOS ILIAS: "Benzalkonium Chlorides: Uses, Regulatory Status, and Microbial Resistance", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 85, no. 13, 1 July 2019 (2019-07-01), US , XP055917898, ISSN: 0099-2240, DOI: 10.1128/AEM.00377-19
J DENT RES, vol. 90, no. 11, 2011, pages 1271 - 1278
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
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