Title:
COMPOSITION FOR REGULATING EXPRESSION OF GENE INVOLVED IN PRODUCTION OR DEGRADATION OF COLLAGEN, ELASTIN, OR HYALURONIC ACID
Document Type and Number:
WIPO Patent Application WO/2022/064839
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a technique for regulating expression of a gene involved in the production or degradation of collagen, elastin, or hyaluronic acid. This problem is solved by using a composition, for regulating the expression of a gene involved in the production or degradation of collagen, elastin or hyaluronic acid, which includes Bifidobacterium Breve M-16V (NITE BP-02622) or a culture supernatant thereof as an active ingredient, wherein the gene is selected from the collagen-degrading enzyme 1 gene (MMP1), the type I collagen gene (COL1A1), the elastin gene (ELN), the hyaluronic acid synthase 1 gene (HAS1), and the hyaluronic acid synthase 2 gene (HAS2).
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Inventors:
MUTOH NATSUMI (JP)
ARAI SATOSHI (JP)
MISAWA ERIKO (JP)
ARAI SATOSHI (JP)
MISAWA ERIKO (JP)
Application Number:
PCT/JP2021/028200
Publication Date:
March 31, 2022
Filing Date:
July 29, 2021
Export Citation:
Assignee:
MORINAGA MILK INDUSTRY CO LTD (JP)
International Classes:
A61K48/00; A23L33/135; A61K35/745; A61P9/14; A61P17/00; A61P19/00; A61P19/02; A61P43/00; C12N1/20; C12N15/12; C12N15/57; C12N15/60
Domestic Patent References:
| WO2011083738A1 | 2011-07-14 |
Foreign References:
| JP2014065669A | 2014-04-17 | |||
| US20160136210A1 | 2016-05-19 | |||
| JP2019167327A | 2019-10-03 | |||
| KR20150056314A | 2015-05-26 | |||
| US20180311144A1 | 2018-11-01 |
Other References:
SHIMIZU, (JZ XIAO) KANETADA; YAESHIMA, TOMOKO: "New topics about the functional studies of bifidobacteria", FOOD CHEMICALS, vol. 23, no. 3, 1 January 2007 (2007-01-01), Japan, pages 19 - 23, XP009535180, ISSN: 0911-2286
DATABASE GNPD MINTEL; 2 July 2018 (2018-07-02), "Bifidobacterium Capsules for Pregnant & Breastfeeding Women", XP055914348, Database accession no. 5795063
DATABASE GNPD MINTEL; 2 July 2018 (2018-07-02), "Bifidobacterium Capsules for Pregnant & Breastfeeding Women", XP055914348, Database accession no. 5795063
Attorney, Agent or Firm:
IP FIRM SHUWA (JP)
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