Title:
COMPOSITION TO IMPROVE MICROBIOME
Document Type and Number:
WIPO Patent Application WO/2019/065038
Kind Code:
A1
Abstract:
[Problem] To provide a composition to improve the microbiome having an excellent effect of proliferating bacteria belonging to the Bifidobacterium genus and bacteria belonging to the Lactobacillus genus, which are useful in the intestines, an effect of increasing the quantity of organic acid in the intestines, and an effect of inhibiting ulcerative colitis. [Solution] A composition for improving the microbiome, characterized by containing, as an active ingredient, a soybean fermentation product or an extract thereof, obtained by fermentation using at least one type from among Rhizopus stolonifer and Rhizopus oryzae belonging to the Rhizopus genus, and a method for producing said composition.
Inventors:
AOKI HIDEYUKI (JP)
KAMEDA TSUYOSHI (JP)
SATO FUMI (JP)
MIYAJIMA AYA (JP)
FUTATSUI KOHEI (JP)
YANAKA NORIYUKI (JP)
KUMRUNGSEE THANUTCHAPORN (JP)
KAMEDA TSUYOSHI (JP)
SATO FUMI (JP)
MIYAJIMA AYA (JP)
FUTATSUI KOHEI (JP)
YANAKA NORIYUKI (JP)
KUMRUNGSEE THANUTCHAPORN (JP)
Application Number:
PCT/JP2018/031579
Publication Date:
April 04, 2019
Filing Date:
August 27, 2018
Export Citation:
Assignee:
IKEDA FOOD RES CO LTD (JP)
UNIV HIROSHIMA (JP)
UNIV HIROSHIMA (JP)
International Classes:
A61K36/062; A23L33/10; A23L33/105; A61K36/48; A61P1/04; A61P1/14; A61K35/745; A61K35/747; A61K131/00
Domestic Patent References:
| WO2017038793A1 | 2017-03-09 |
Foreign References:
| JP2013107872A | 2013-06-06 |
Other References:
UTAMA,ZAKI ET AL.: "Tempe Consumption Modulates Fecal Secondary Bile Acids, Mucins, Immunoglobulin A, Enzyme Activities, and Cecal Microflora and Organic Acids in Rats", PLANT FOODS FOR HUMAN NUTRITION, vol. 68, no. 2, 2013, pages 177 - 183, XP035364198, ISSN: 0921-9668, DOI: doi:10.1007/s11130-013-0357-x
NISHISE, HIROSHI ET AL.: "Isolation of Rhizopus sp. strains from Ragi tempe", BULLETIN OF KOSHIEN UNIVERSITY, vol. 35, 2008, pages 35 - 38, ISSN: 1881-5731
LIAO, WEI ET AL.: "Studying Pellet Formation of a Filamentous Fungus Rhizopus oryzae to Enhance Organic Acid Production", APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, vol. 136, no. 140, 2007, pages 689 - 701, XP002655354, ISSN: 0273-2289, DOI: doi:10.1007/s12010-007-9089-4
TAKESHITA,KOZUE ET AL.: "A Single Species of Clostridium Subcluster XIVa Decreased in Ulcerative Colitis Patients", INFLAMMATORY BOWEL DISEASES, vol. 22, no. 12, 2016, pages 2802 - 2810, ISSN: 1536-4844
YOGO,TAKUYA ET AL.: "Influence of Dried Okara-Tempeh on the Composition and Metabolites of Fecal Microbiota in Dogs", INTERNATIONAL JOURNAL OF APPLIED RESEARCH IN VETERINARY MEDICINE, vol. 9, no. 2, 2011, pages 176 - 183, XP055587848, ISSN: 1542-2666
NISHISE, HIROSHI ET AL.: "Isolation of Rhizopus sp. strains from Ragi tempe", BULLETIN OF KOSHIEN UNIVERSITY, vol. 35, 2008, pages 35 - 38, ISSN: 1881-5731
LIAO, WEI ET AL.: "Studying Pellet Formation of a Filamentous Fungus Rhizopus oryzae to Enhance Organic Acid Production", APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, vol. 136, no. 140, 2007, pages 689 - 701, XP002655354, ISSN: 0273-2289, DOI: doi:10.1007/s12010-007-9089-4
TAKESHITA,KOZUE ET AL.: "A Single Species of Clostridium Subcluster XIVa Decreased in Ulcerative Colitis Patients", INFLAMMATORY BOWEL DISEASES, vol. 22, no. 12, 2016, pages 2802 - 2810, ISSN: 1536-4844
YOGO,TAKUYA ET AL.: "Influence of Dried Okara-Tempeh on the Composition and Metabolites of Fecal Microbiota in Dogs", INTERNATIONAL JOURNAL OF APPLIED RESEARCH IN VETERINARY MEDICINE, vol. 9, no. 2, 2011, pages 176 - 183, XP055587848, ISSN: 1542-2666
Attorney, Agent or Firm:
ABE Masahiro (JP)
Download PDF:
Previous Patent: COMPONENT-EQUIPPED BODY AND ELECTRONIC APPARATUS
Next Patent: REFRIGERATION CYCLE DEVICE
Next Patent: REFRIGERATION CYCLE DEVICE