Title:
COMPOSITION AND USE THEREOF IN PREPARATION OF CELL MEMBRANE
Document Type and Number:
WIPO Patent Application WO/2023/245813
Kind Code:
A1
Abstract:
Provided are a composition and the use thereof in preparation of a cell membrane. The composition comprises an ITS cell culture additive, dexamethasone and vitamin C. The composition can be used to prepare a cell membrane by means of a general cell culture dish; and compared with the conventional preparation of the cell membrane by means of a temperature-sensitive culture dish, by adopting the composition, the cost of preparing a cell membrane can be greatly reduced, the number of cells is increased, and the success rate of preparing the cell membrane is improved. The present invention can be better used in the fields of tissue engineering and regenerative medicine (repairing damaged tissues and/or organs, and constructing three-dimensional tissues and/or organs), and is expected to achieve commercial large-scale production.
Inventors:
GAO BOTAO (CN)
GUAN SHUWEN (CN)
GUAN SHUWEN (CN)
Application Number:
PCT/CN2022/108694
Publication Date:
December 28, 2023
Filing Date:
July 28, 2022
Export Citation:
Assignee:
INST OF BIOLOGICAL AND MEDICAL ENGINEERING GUANGDONG ACADEMY OF SCIENCES (CN)
International Classes:
C12N5/0775; A61L27/38; C12N5/077
Foreign References:
| CN102899287A | 2013-01-30 | |||
| CN108676773A | 2018-10-19 | |||
| CN105695402A | 2016-06-22 | |||
| CN105132368A | 2015-12-09 | |||
| CN108384752A | 2018-08-10 | |||
| US20150093428A1 | 2015-04-02 |
Other References:
HUIMING YANG, YU XING; FANG YUHUI: "Effects of chondrocyte membrane artificial biological pancreas prepared by microencapsulating rat pancreatic islet cells with mouse auricular chondrocyte on blood glucose level in diabetic mice", JOURNAL OF MEDICAL SCIENCE YANBIAN UNIVERSITY, vol. 42, no. 2, 26 June 2019 (2019-06-26), pages 82 - 85, XP093119898
MIYAHARA YOSHINORI, NAGAYA NORITOSHI, KATAOKA MASAHARU, YANAGAWA BOBBY, TANAKA KOICHI, HAO HIROYUKI, ISHINO KOZO, ISHIDA HIDEYUKI,: "Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarction", NATURE MEDICINE, NATURE PUBLISHING GROUP US, NEW YORK, vol. 12, no. 4, 1 April 2006 (2006-04-01), New York, pages 459 - 465, XP093119899, ISSN: 1078-8956, DOI: 10.1038/nm1391
MIYAHARA YOSHINORI, NAGAYA NORITOSHI, KATAOKA MASAHARU, YANAGAWA BOBBY, TANAKA KOICHI, HAO HIROYUKI, ISHINO KOZO, ISHIDA HIDEYUKI,: "Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarction", NATURE MEDICINE, NATURE PUBLISHING GROUP US, NEW YORK, vol. 12, no. 4, 1 April 2006 (2006-04-01), New York, pages 459 - 465, XP093119899, ISSN: 1078-8956, DOI: 10.1038/nm1391
Attorney, Agent or Firm:
JIAQUAN IP LAW (CN)
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