Title:
COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2019/016988
Kind Code:
A1
Abstract:
Provided is a composition for improving atrophy of the hippocampus in the human brain, a composition for increasing the volume of the hippocampus in the human brain, or a composition for increasing the volume of the human brain, in which coenzyme Q10 and earthworm dry powder are employed as active ingredients. A reduction-type coenzyme Q10 is employed as the coenzyme Q10. By doing so, the present invention provides a composition that can be employed in the prevention or/and treatment of brain-related diseases, such as Alzheimer's disease, dementia, Parkinson's disease, myalgic encephalomyelitis, multiple system atrophy, etc. The present invention provides, in particular, a composition that can be employed in the prevention or treatment of atrophy of the hippocampus in the brain.
Inventors:
NAOI NORIYUKI (JP)
MATSUOKA TADASHI (JP)
MATSUOKA TADASHI (JP)
Application Number:
PCT/JP2018/005201
Publication Date:
January 24, 2019
Filing Date:
February 15, 2018
Export Citation:
Assignee:
ENZYM CO LTD (JP)
International Classes:
A61K35/62; A61K31/09; A61K31/122; A61P25/28; A61P43/00
Domestic Patent References:
| WO2017014162A1 | 2017-01-26 | |||
| WO2015108014A1 | 2015-07-23 |
Foreign References:
| JPH02212421A | 1990-08-23 |
Other References:
LI, G. ET AL.: "Diet supplement CoQ10 delays brain atrophy in aged transgenic mice with mutations in the amyloid precursor protein: An in vivo volume MRI study", BIOFACTORS, vol. 32, no. 1-4, 2008, pages 169 - 178
15 June 2017 (2017-06-15), Retrieved from the Internet
15 June 2017 (2017-06-15), Retrieved from the Internet
Attorney, Agent or Firm:
NISHIHARA,Hironori (JP)
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