COMPOSITIONS OF A CYCLOOXYGENASE-2 SELECTIVE INHIBITOR AND A PHOSPHODIESTERASE INHIBITOR FOR THE TREATMENT OF ISCHEMIC MEDIATED CENTRAL NERVOUS SYSTEM DISORDERS OR INJURY

Title:

COMPOSITIONS OF A CYCLOOXYGENASE-2 SELECTIVE INHIBITOR AND A PHOSPHODIESTERASE INHIBITOR FOR THE TREATMENT OF ISCHEMIC MEDIATED CENTRAL NERVOUS SYSTEM DISORDERS OR INJURY

Document Type and Number:

WIPO Patent Application WO2005018563

Kind Code:

A3

Abstract:

The present invention provides compositions and methods for the treatment of central nervous system disorders. In some aspects, the invention provides a combination therapy for the treatment of a central nervous system ischemic mediated disorder comprising the administration to a subject of a PDE inhibitor in combination with a cyclooxygenase-2 selective inhibitor.

Inventors:

STEPHENSON DIANE T (US)

Application Number:

PCT/US2004/027146

Publication Date:

December 29, 2005

Filing Date:

August 20, 2004

Export Citation:

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Assignee:

PHARMACIA CORP (US)
STEPHENSON DIANE T (US)

International Classes:

A61K31/18; A61K31/35; A61K31/415; A61K31/42; A61K31/44; A61K31/45; A61K31/50; A61K; (IPC1-7): A61K31/42; A61K31/44; A61K31/35; A61K31/45

Foreign References:

US20030069169A1	2003-04-10
US5466823A	1995-11-14
US5932598A	1999-08-03
US6291523B1	2001-09-18
US6034256A	2000-03-07

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