COMPOSITIONS OF A CYCLOOXYGENASE-2 SELECTIVE INHIBITOR AND A LOW-MOLECULAR-WEIGHT HEPARIN FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DAMAGE

Title:

COMPOSITIONS OF A CYCLOOXYGENASE-2 SELECTIVE INHIBITOR AND A LOW-MOLECULAR-WEIGHT HEPARIN FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DAMAGE

Document Type and Number:

WIPO Patent Application WO2005018564

Kind Code:

A3

Abstract:

The present invention provides compositions and methods for the treatment of central nervous system damage in a subject. More particularly, the invention provides a combination therapy for the treatment of a central nervous system ischemic condition or a central nervous system traumatic injury comprising the administration to a subject of a low-molecular-weight heparin in combination with a cyclooxygenase-2 selective inhibitor.

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Inventors:

STEPHENSON DIANE T (US)

Application Number:

PCT/US2004/027148

Publication Date:

June 09, 2005

Filing Date:

August 20, 2004

Export Citation:

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Assignee:

PHARMACIA CORP (US)
STEPHENSON DIANE T (US)

International Classes:

A01N29/00; A61K31/18; A61K31/33; A61K31/415; A61K31/50; A61K31/70; A61K31/727; A61P9/10; C08B37/10; A61K; (IPC1-7): A01N29/00; A61K31/33; A61K31/70; A61K31/727; C08B37/10

Foreign References:

US6585995B1	2003-07-01
US6596747B2	2003-07-22

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