Title:
COMPOSITIONS FOR DELIVERING PEPTIDE YY AND PYY AGONISTS
Document Type and Number:
WIPO Patent Application WO2004104018
Kind Code:
A3
Abstract:
The present invention provides a composition (e.g., a pharmaceutical composition) comprising at least one delivery agent compound and at least one of peptide YY (PYY) and a PYY agonist. Preferably, the composition includes a therapeutically effective amount of peptide YY or the PYY agonist and the delivery agent compound. The composition of the present invention facilitates the delivery of PYY, a PYY agonist, or a mixture thereof and increases its bioavailability compared to administration without the delivery agent compound. PPY and PYY agonists possess activity as agents to reduce nutrient availability, including reduction of food intake.
Inventors:
DINH STEVE (US)
WANG HUAIZHEN (US)
GOMEZ-ORELLANA M ISABEL (US)
WANG HUAIZHEN (US)
GOMEZ-ORELLANA M ISABEL (US)
Application Number:
PCT/US2004/015162
Publication Date:
May 06, 2005
Filing Date:
May 14, 2004
Export Citation:
Assignee:
EMISPHERE TECH INC (US)
DINH STEVE (US)
WANG HUAIZHEN (US)
GOMEZ-ORELLANA M ISABEL (US)
DINH STEVE (US)
WANG HUAIZHEN (US)
GOMEZ-ORELLANA M ISABEL (US)
International Classes:
A61K31/195; A61K38/00; A61K38/17; C07K; (IPC1-7): A61K38/00
Domestic Patent References:
| WO2001032596A1 | 2001-05-10 |
Foreign References:
| US5650386A | 1997-07-22 |
Other References:
BATTERHAM R.L. ET AL.: "Gut hormone PYY [3-36] physiologically inhibits food intake", NATURE, vol. 418, 8 August 2002 (2002-08-08), pages 650 - 654, XP002984562
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