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Title:
COMPOUND AS GLP-1 RECEPTOR AGONIST AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/066356
Kind Code:
A1
Abstract:
Provided in the present application are a compound as represented by formula (I) and the use thereof. The compound as represented by formula (I) provided in the present application can be used as an effective glucagon-like peptide-1 (GLP-1) receptor agonist, has excellent GLP-1R receptor agonistic activity and a significant effect of reducing blood glucose, has good pharmacokinetic characteristics, and provides more choices for the prevention and/or treatment of diseases, conditions or disorders related to GLP-1 activity, thereby having good clinical application prospects.

Inventors:
WANG TONG (CN)
HAO YAN (CN)
TANG MULIN (CN)
DING JUPING (CN)
YU QIANG (CN)
CHEN BIN (CN)
OUYANG ZHENWU (CN)
Application Number:
PCT/CN2022/126581
Publication Date:
April 27, 2023
Filing Date:
October 21, 2022
Export Citation:
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Assignee:
CGENETECH SUZHOU CHINA CO LTD (CN)
International Classes:
C07D405/14; A61K31/4427; A61K31/497; A61P3/10; A61P9/00; C07D401/14; C07D487/04
Domestic Patent References:
WO2022192430A12022-09-15
WO2022109182A12022-05-27
WO2022111624A12022-06-02
WO2021018023A12021-02-04
Foreign References:
CN113773310A2021-12-10
CN113227068A2021-08-06
CN112566637A2021-03-26
CN110325530A2019-10-11
Attorney, Agent or Firm:
BEIJING YUEHE INTELLECTUAL PROPERTY AGENCY CO., LTD (CN)
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