Title:
COMPOUNDS AND METHODS FOR DIAGNOSING AND TREATING AMYLOID-RELATED CONDITIONS
Document Type and Number:
WIPO Patent Application WO2002024652
Kind Code:
B1
Abstract:
The invention provides methods for diagnosing and treating amyloid-related conditions and compounds useful for the same. The invention provides for detecting, imaging, monitoring, diagnosing, and treating conditions characterized by the binding or aggregation of amyloid fibrils. More particularly, the invention relates to using quinolinehydrazone compounds for diagnosing and treating amyloidotic conditions and also as an antioxidant.
Inventors:
RAUB THOMAS J
TANIS STEVEN P
BUHL ALLEN EDWIN
CARTER DONALD BAINBRIDGE
BANDIERA TIZIANO
LANSEN JACQUELINE
PELLERANO CESARE
SAVINI LUISA
TANIS STEVEN P
BUHL ALLEN EDWIN
CARTER DONALD BAINBRIDGE
BANDIERA TIZIANO
LANSEN JACQUELINE
PELLERANO CESARE
SAVINI LUISA
Application Number:
PCT/US2001/029010
Publication Date:
June 27, 2002
Filing Date:
September 17, 2001
Export Citation:
Assignee:
UPJOHN CO (US)
PHARMACIA & UPJOHN SPA (IT)
PHARMACIA & UPJOHN SPA (IT)
International Classes:
A61K31/47; A61K45/06; A61K51/04; C07D215/38; (IPC1-7): C07D215/38; A61K31/47
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