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Title:
COMPOUNDS AND METHODS OF TREATING CANCERS
Document Type and Number:
WIPO Patent Application WO/2022/073469
Kind Code:
A1
Abstract:
This disclosure relates to GSPT1 degrader compounds (e.g. small molecule compounds), compositions comprising one or more of the compounds, and to methods of use the compounds for the treatment of certain disease in a subject in need thereof. The disclosure also relates to methods for identifying such compounds.

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Inventors:
LIU JING (US)
PLEWE MICHAEL BRUNO (US)
WANG JIALIANG (US)
HAN XIAORAN (CN)
CHEN LIQUN (CN)
YANG TING (CN)
ZHANG CHENGWEI (CN)
Application Number:
PCT/CN2021/122530
Publication Date:
April 14, 2022
Filing Date:
October 07, 2021
Export Citation:
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Assignee:
CULLGEN SHANGHAI INC (CN)
International Classes:
C07D401/14; A61K31/454; A61K31/535; A61P35/00; C07D401/04
Domestic Patent References:
WO2019006299A12019-01-03
WO2018118947A12018-06-28
WO2020038415A12020-02-27
WO2019042442A12019-03-07
WO2019241271A12019-12-19
WO2020200291A12020-10-08
WO2020242960A12020-12-03
Foreign References:
US20200306273A12020-10-01
US20190062309A12019-02-28
US20180264000A12018-09-20
Attorney, Agent or Firm:
AFD CHINA INTELLECTUAL PROPERTY LAW OFFICE (CN)
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