Title:
COMPOUNDS WHICH MIMIC THE CHEMICAL AND BIOLOGICAL PROPERTIES OF DISCODERMOLIDE
Document Type and Number:
WIPO Patent Application WO/2003/013502
Kind Code:
A1
Abstract:
Compounds which mimic the chemical and/or biological activity of discodermolide are provided.
Inventors:
SMITH AMOS B III (US)
BEAUCHAMP THOMAS J (US)
LAMARCHE MATTHEW J (US)
RUCKER PAUL (US)
BEAUCHAMP THOMAS J (US)
LAMARCHE MATTHEW J (US)
RUCKER PAUL (US)
Application Number:
PCT/US2002/024932
Publication Date:
February 20, 2003
Filing Date:
August 06, 2002
Export Citation:
Assignee:
UNIV PENNSYLVANIA (US)
International Classes:
A61K31/047; A61K31/121; C07D213/50; A61K31/27; A61K31/351; A61K31/366; A61K31/422; A61K31/427; A61K31/4402; A61K31/4409; A61P35/00; C07C33/30; C07C49/248; C07C271/12; C07D303/30; C07D309/10; C07D309/30; C07D309/32; C07D309/38; C07D319/06; C07D407/06; C07D413/06; C07D417/06; C07F9/655; C07H15/04; C07H15/203; (IPC1-7): A61K31/25; C07D309/30
Foreign References:
| US5010999A | 1991-04-30 | |||
| US5681847A | 1997-10-28 |
Other References:
HUNG ET AL.: "Synthesis of discodermolides useful for investigating microtuble binding and stabilization", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 118, 1996, pages 11054 - 11080, XP000652059
See also references of EP 1414434A4
See also references of EP 1414434A4
Attorney, Agent or Firm:
Deluca, Mark (One Liberty Place 46th Floo, Philadelphia PA, US)
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