Title:
COPPER @ RHUBARB ANTHRAQUINONE METAL ORGANIC FRAMEWORK COMPOSITE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/218129
Kind Code:
A1
Abstract:
Disclosed are a copper @ rhubarb anthraquinone metal organic framework composite and the use thereof. The copper @ rhubarb anthraquinone metal organic framework composite comprises the following components in parts by mass: 1-600 parts of a rhubarb anthraquinone compound and 1-1200 parts of an alkaline copper salt. The copper @ rhubarb anthraquinone metal organic framework composite has both physical and chemical sunscreen functions, has a good anti-ultraviolet damage effect, can remarkably protect skin, and can be used as an additive ingredient in sunscreen and makeup. In addition, the copper @ rhubarb anthraquinone metal organic framework composite is synthesized with the rhubarb anthraquinone compound, which is a natural Chinese herbal ingredient, as a raw material, thereby reducing the problem caused by the permeation of general chemical sunscreen ingredients into the human body in terms of safety.
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Inventors:
XIAO JISHENG (CN)
SU XIAOYING (CN)
LIU SIJUN (CN)
SU XIAOYING (CN)
LIU SIJUN (CN)
Application Number:
PCT/CN2020/131025
Publication Date:
November 04, 2021
Filing Date:
November 24, 2020
Export Citation:
Assignee:
GUANGZHOU UNIV OF CHINESE MEDICINE GUANGZHOU INSTITUTE OF CHINESE MEDICINE (CN)
International Classes:
A61K8/35; A61K8/19; A61K8/368; A61Q17/04
Domestic Patent References:
| WO2019238261A1 | 2019-12-19 |
Foreign References:
| CN111494226A | 2020-08-07 | |||
| CN110981909A | 2020-04-10 |
Other References:
PAN XIAOLI: "Synthesis,Characterization and Biological Activity of Metal Complexes on the Basisd of Anthraquinone in Rhubarb", CHINESE DOCTORAL DISSERTATIONS FULL-TEXT DATABASE, 1 April 2014 (2014-04-01), pages 1 - 161, XP055861843
PAN XIAO-LI;XIANG HUI;XIE YUN-FEI;ZHANG CONG-EN;DONG XIAO-PING: "The Compound Confirm and Antioxidant Activity of Emodin-copper(Ⅱ)Metal Complex", LISHIZHEN MEDICINE AND MATERIA MEDICA RESEARCH, vol. 24, no. 12, 20 December 2013 (2013-12-20), pages 2892 - 2894, XP055861859, ISSN: 1008-0805, DOI: 10.3969/j.issn.1008-0805.2013.12.029
ZHAO FANG,LIANG HUI ,CHENG HUI,WANG JUN,ZHAO WEN-HUI: "Interaction of Rhein-Cu(II) Complexes with Bovine Serum Albumin", CHEMICAL JOURNAL OF CHINESE UNIVERSITIES, vol. 32, no. 6, 10 June 2011 (2011-06-10), CN, pages 1277 - 1283, XP055861870, ISSN: 0251-0790
PAN XIAO-LI;XIANG HUI;XIE YUN-FEI;ZHANG CONG-EN;DONG XIAO-PING: "The Compound Confirm and Antioxidant Activity of Emodin-copper(Ⅱ)Metal Complex", LISHIZHEN MEDICINE AND MATERIA MEDICA RESEARCH, vol. 24, no. 12, 20 December 2013 (2013-12-20), pages 2892 - 2894, XP055861859, ISSN: 1008-0805, DOI: 10.3969/j.issn.1008-0805.2013.12.029
ZHAO FANG,LIANG HUI ,CHENG HUI,WANG JUN,ZHAO WEN-HUI: "Interaction of Rhein-Cu(II) Complexes with Bovine Serum Albumin", CHEMICAL JOURNAL OF CHINESE UNIVERSITIES, vol. 32, no. 6, 10 June 2011 (2011-06-10), CN, pages 1277 - 1283, XP055861870, ISSN: 0251-0790
Attorney, Agent or Firm:
GUANGZHOU HUAXUE INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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