Title:
CRYSTAL FORM OF PIPERAZINE AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/022206
Kind Code:
A1
Abstract:
The present invention relates to the field of chemical pharmaceuticals, relates to a crystal form of a piperazine amide derivative, a preparation method therefor and a use thereof, specifically relates to crystal forms A, B, C, D, and E of a compound of formula (I), a preparation method therefor, and a pharmaceutical composition and use thereof, and solves the problems of small granularity, poor fluidity, poor stability and the like of the compound of formula (I) present in an amorphous form. The crystal form prepared by the present invention and the pharmaceutical composition thereof can be used for preparing a drug for treating diseases such as cancer.
Inventors:
CHEN LIANWEI (CN)
ZHAO MEIYU (CN)
LI NA (CN)
SHI ZHENJUAN (CN)
ZHAO MEIYU (CN)
LI NA (CN)
SHI ZHENJUAN (CN)
Application Number:
PCT/CN2023/108281
Publication Date:
February 01, 2024
Filing Date:
July 20, 2023
Export Citation:
Assignee:
ZHEJIANG HISUN PHARM CO LTD (CN)
International Classes:
C07D403/04; A61K31/506; A61P35/00
Domestic Patent References:
| WO2020207419A1 | 2020-10-15 | |||
| WO2016127074A1 | 2016-08-11 | |||
| WO2017161269A1 | 2017-09-21 | |||
| WO2018017983A1 | 2018-01-25 |
Foreign References:
| CN108473468A | 2018-08-31 |
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