CRYSTALLINE FORM OF A SUBSTITUTED PYRROLIDINE COMPOUND

Title:

CRYSTALLINE FORM OF A SUBSTITUTED PYRROLIDINE COMPOUND

Document Type and Number:

WIPO Patent Application WO2005123670

Kind Code:

A3

Abstract:

The invention provides a crystalline naphthalene-1,5-disulfonic acid salt of 2-[(S)-1-(8-methylaminooctyl)pyrrolidin-3-yl]-2,2-diphenylacetamide or a solvate thereof. This invention also provides pharmaceutical compositions comprising the salt or prepared using the salt; processes and intermediates for preparing the salt; and methods of using the salt to treat a pulmonary disorder.

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Inventors:

LI LI (US)
CHAO ROBERT S (US)
HUGHES ADAM (US)
JI YU-HUA (US)
KHOSSRAVI DAVAR (US)
ZHANG WEIJIANG (US)

Application Number:

PCT/US2005/020282

Publication Date:

February 09, 2006

Filing Date:

June 09, 2005

Export Citation:

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Assignee:

THERAVANCE INC (US)
LI LI (US)
CHAO ROBERT S (US)
HUGHES ADAM (US)
JI YU-HUA (US)
KHOSSRAVI DAVAR (US)
ZHANG WEIJIANG (US)

International Classes:

C07D207/09; A61K31/40; A61P11/06; A61P11/08; C07D207/30

Domestic Patent References:

WO2004041806A2

2004-05-21

Foreign References:

US20040254219A1

2004-12-16

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